血清免疫球蛋白检验在肝衰竭诊断中的临床效果评价

Clinical Evaluation of Serum Immunoglobulin Test in Diagnosis of Liver Failure

目的探讨血清免疫球蛋白检验在肝衰竭诊断中的临床效果。方法选取该院2017年3月-2019年3月收治的肝衰竭患者20例作为观察组,选取同期健康体检者20名作为对照组,全部患者均行血清免疫球蛋白检验,比较两组的检验结果,分析不同程度肝衰竭患者的免疫球蛋白指标变化。结果观察组的免疫球蛋白IgA(10.59±1.76)g/L、IgG(26.21±5.35)g/L和IgM(2.96±0.21)g/L高于对照组的(3.14±1.29)g/L、(10.78±1.59)g/L、(1.38±0.57)g/L(t=15.268、12.364、11.632,P<0.05);观察组发病1~10 d、11~30 d和31~45 d患者的IgA、IgG、IgM比较,差异有统计学意义(t=12.202、11.617、12.990,P<0.05)。结论在肝衰竭诊断中应用血清免疫球蛋白检验可为医师鉴别肝衰竭病例提供参照,明确患者病情严重程度,具有重要的应用价值。

Objective To investigate the clinical effect of serum immunoglobulin test in the diagnosis of liver failure.Methods 20 patients with liver failure treated in the hospital from March 2017 to March 2019 were selected as the observation group, and 20 healthy pepole were selected as the control group. All patients were tested for serum immunoglobulin, and the results of the two groups were compared, changes in immunoglobulin indicators were analyzed.Results The immunoglobulin IgA(10.59±1.76) g/L, IgG(26.21±5.35) g/L, and IgM(2.96±0.21) g/L in the observation group were higher than those in the control group(3.14±1.29) g/L,(10.78±1.59) g/L,(1.38±0.57) g/L(t=15.268, 12.364,11.632,P <0.05), There was significant difference between IgA, IgG and IgM(t =12.202, 11.617, 12.990,P <0.05).Conclusion The application of serum immunoglobulin test in the diagnosis of liver failure can provide a reference for physicians to identify cases of liver failure, and clarify the severity of the patient’s condition, which has important application value.