摘要
目的了解安康市2017年产妇新生儿脐带血风疹抗体水平。方法在安康市10个县区选择16-45岁产妇,采集新生儿脐带血,采用间接酶联免疫吸附试验(ELISA)检测风疹IgG抗体,分析抗体阳性率。结果安康市2017年产妇新生儿脐带血风疹IgG抗体总阳性率为89.87%(763/849)。各年龄组产妇新生儿脐带血风疹IgG抗体阳性率在87.32%-90.91%之间(χ^2=3.18,P>0.05),抗体阳性率随产妇年龄增大而呈下降趋势;各县区抗体阳性率在83.33%-93.00%之间(χ^2=81.06,P<0.05);乡镇集中接种、村级接种地区的抗体阳性率分别为92.45%、87.14%(χ^2=6.32,P<0.05)。结论安康市2017年产妇新生儿脐带血风疹抗体水平较高,提示产妇可能曾有自然感染;建议育龄妇女孕前接种含风疹成分疫苗。
Objective To determine rubella antibody levels in umbilical cord blood of newborns in Ankang city in 2017.Methods We enrolled 16-45-year-old mothers from 10 counties of Ankang to obtain neonatal umbilical cord blood.We tested cord blood for rubella IgG antibody using indirect ELISA to determine antibody positivity.Results The overall rubella IgG antibody positivity rate was 89.87%(763/849)in umbilical cord blood of newborns in Ankang in2017.Positivity rates by maternal age at delivery ranged from 87.32%to 90.91%(χ^2=3.18,P>0.05),decreasing with increasing maternal age.Positivity rates by county ranged from 83.33%to 93.00%(χ^2=81.06,P<0.05).The positivity rate was 92.45%in township-vaccination areas and 87.14%in village-vaccination areas(χ^2=6.32,P<0.05).Conclusions Rubella antibody levels in umbilical cord blood of newborns were high in Ankang in 2017,indicating past natural infections among some mothers.We recommend rubella vaccination for childbearing-age women.
作者
万春阁
罗延琪
陈磊
戴小强
Wan Chunge;Luo Yanqi;Chen Lei;Dai Xiaoqiang(Ankang Municipal Center for Disease Control and Prevention,Ankang 725000,Shaanxi,China)
出处
《中国疫苗和免疫》
北大核心
2020年第2期190-192,共3页
Chinese Journal of Vaccines and Immunization
关键词
风疹
IGG抗体
脐带血
新生儿
Rubella
IgG antibody
Umbilical cord blood
Newborn