甲状腺功能疾病辅助生殖妊娠患者产后出血的相关研究

Study on Postpartum Hemorrhage in Patients with Thyroid Dysfunction and Assisted Reproductive Pregnancy

目的探讨甲状腺功能疾病辅助生殖妊娠患者产后出血的相关研究。方法该项研究对象便利选择该院2017年1月—2019年2月确诊收治的60例甲状腺功能疾病妊娠患者设为研究组,选择同期60例甲状腺功能正常的患者设为对照组。统计分析两组患者各项临床指标,对甲状腺功能疾病辅助生殖妊娠患者的妊娠结局以及产后出血状况予以分析。结果对照组出血量100~200 mL,出血量/血容量15%~25%;研究组出血量200~300 mL,出血量/血容量35%~45%。研究组胎膜早破、产后出血、新生儿窒息并发症相较于对照组明显较高,两组产后出血量结果,对比差异有统计学意义(t=13.927,P=0.000<0.05)。结论甲状腺功能减退会增加患者产后出血的风险,同时影响妊娠结局,故而应该对妊娠期患者给予甲状腺功能的改善治疗,减少产后出血风险。

Objective To investigate the correlation of postpartum hemorrhage in assisted reproductive pregnancy(ARP)patients with thyroid diseases.Methods 60 pregnant women with thyroid diseases diagnosed and treated in the hospital from January 2017 to February 2019 were convenient selected as the study group,and 60 patients with normal thyroid function were selected as the control group during the same period.Statistical analysis of the clinical indicators of the two groups of patients,the pregnancy outcome and postpartum hemorrhage in patients with thyroid disease assisted reproductive pregnancy were analyzed.Results The bleeding volume 100~200 mL,bleeding volume/blood volume 15%~25%in the control group,and bleeding volume 200~300 mL,bleeding volume/blood volume 35%~45%in the study group.The complications of premature rupture of membranes,postpartum hemorrhage,neonatal asphyxia and premature rupture of membranes in the study group were significantly higher than those in the control group.The results of postpartum hemorrhage test between the two groups showed significant difference(t=13.927,P=0.000<0.05).Conclusion Hypothyroidism may increase the risk of postpartum hemorrhage and affect the outcome of pregnancy.Therefore,the improvement of thyroid function in pregnant women should be given to reduce the risk of postpartum hemorrhage.