孕期服用醋酸钙对孕产妇骨密度的影响

Effects of Taking Calcium Acetate During Pregnancy on Maternal Bone Mineral Density

目的指导孕期妇女服用醋酸钙,观察服用醋酸钙对孕产妇骨密度的影响。方法在2018年1月—2019年1月该院收治的妊娠期妇女中,方便选择其中的80名作为研究对象,按照来院的先后顺序将其分为实验1组和实验2组,每组中安排40名妊娠期妇女。把持续补钙模式应用在实验1组,把阶段性补钙模式在实验2组中应用,两组孕妇都是服用醋酸钙胶囊(金丐)。对两组孕期妇女治疗干预前后骨密度的改善幅度、骨质疏松不良反应的发生率进行比较。结果该次研究结果显示,实验1组干预前骨密度(0.672±0.110)g/cm2、实验2组干预前骨密度(0.684±0.109)g/cm2(t=1.005,P>0.05),实验1组干预后骨密度(0.713±0.145)g/cm2,实验2组干预后骨密度(0.889±0.115)g/cm2(t=12.356,P<0.05),干预后与实验1组相比,实验2组孕妇的骨密度指标改善较好,差异有统计学意义(P<0.05)。实验1组和实验2组的孕妇中分别有8例和1例发生了骨质疏松,骨质疏松的发生率分别为20.00%和2.50%,差异有统计学意义(χ2=10.472,P<0.05)。结论为妊娠期妇女实施阶段性补醋酸钙模式具有非常大的价值和意义,能有效促进孕妇骨密度的改善,降低不良反应的发生率,提升孕妇的满意度,值得在临床中推广应用。

Objective To instruct pregnant women to take calcium acetate and observe the effect of calcium acetate on bone mineral density of pregnant and lying-in women.Methods From January 2018 to January 2019,80 pregnant women in the hospital were convenient selected as the study subjects.They were divided into experimental group 1 and experimental group 2 according to the order of coming to our hospital.40 pregnant women were arranged in each group.The continuous calcium supplementation model was applied in group 1 and the periodic calcium supplementation model was applied in group 2.Both groups of pregnant women took calcium acetate capsules(Jinpi).The improvement of bone mineral density and the incidence of adverse effects of osteoporosis were compared between the two groups before and after treatment intervention.Results The results of this study showed that the bone mineral density of experimental group 1 before intervention was(0.672±0.110)g/cm2,that of experimental group 2 before intervention was(0.684±0.109)g/cm2(t=1.005,P>0.05),that of experimental group 1 after intervention was(0.713±0.145)g/cm2,and that of experimental group 2 after intervention was(0.889±0.115)g/cm2(t=12.356,P<0.05).The bone mineral density of pregnant women in the two groups improved better,with statistically significant difference(P<0.05).Among the pregnant women in experiment 1 group and experiment 2 group,there were 8 cases and 1 case of osteoporosis,the incidence of osteoporosis was 20.00%and 2.50%,respectively,the difference was statistically significant(χ2=10.472,P<0.05).Conclusion It is of great value and significance to implement the model of calcium acetate supplementation in stages for pregnant women.It can effectively improve the bone mineral density of pregnant women,reduce the incidence of adverse reactions and improve the satisfaction of pregnant women.It is worth popularizing and applying in clinical practice.