临床药师参与1例肝肾联合移植术后他克莫司的用药监护

Pharmaceutical care for a patient treated with tacrolimus after liver and renal transplantation

临床药师以1例肝肾联合移植术后移植受者的他克莫司血药浓度波动为切入点,通过基因检测技术、治疗药物监测等精准化药学手段,为患者提供个体化的药物服务,制订个体化的他克莫司治疗方案,指导临床合理用药。在患者的临床治疗过程中,临床药师对肝肾联合移植受者开展药学服务实践并发挥作用,建立肝肾联合移植受者精准化药学服务的模式,保证了患者用药的安全性和有效性。

With the assistance of advanced and precise pharmaceutical means,such as gene detection and therapeutic drug monitoring,clinical pharmacists measured the fluctuations of tacrolimus blood concentrations in one transplant recipient after combined liver-kidney transplantation as the breakthrough point,to provide individualized drug services for patients,to develop individualized tacrolimus treatment plan,and to guide the clinical rational drug use.In the clinical treatment,pharmaceutical care was provided and it played a role in the recipient with combined liver-kidney transplant.A precise pharmaceutical care model for combined liver-kidney transplantation recipient has been established,to ensure the safety and efficacy of the medication.