频域光相干断层扫描不同测量范围对正常健康眼脉络膜血管指数的影响

Assessment of choroidal vascularity index in healthy eyes of different subfoveal choroidal areas on enhanced depth imaging optical coherence tomography

目的观察频域OCT不同测量范围对正常健康眼脉络膜血管指数(CVI)的影响。方法回顾性临床研究。2017年10月至2018年5月于北京友谊医院眼科就诊且经检查未发现眼部异常的87名健康者174只眼纳入研究。均接受频域OCT深度增强成像技术经黄斑中心凹单线扫描,对采集的脉络膜图像经二值化处理后,计算以黄斑中心凹为中心半径750、1500、3000、4500μm范围的CVI,并据此分组。组间CVI比较行重复测量方差分析。结果750μm组、1500μm组、3000μm组、4500μm组CVI平均值分别为0.681±0.003、0.678±0.002、0.677±0.002、0.676±0.002。两两比较,750μm组和4500μm组差值为0.005±0.002,差异有统计学意义(P=0.009);其余两两比较结果,差异均无统计学意义(P>0.05)。结论正常健康眼距黄斑中心凹距离不同,CVI不同。

Objective To observe the effect of spectral-domain OCT with different subfoveal choroidal areas on choroid vascular index(CVI)in normal healthy eyes.Methods Retrospective clinical study.From October 2017 to May 2018,174 eyes of 87 healthy people who visited in the Ophthalmology Department of Beijing Friendship Hospital and had no eye abnormalities were included in the study.All patients received single line scan of macular fovea by enhanced depth imaging OCT.After binary processing of the collected choroidal images,CVI as the center radius of 750,1500,3000 and 4500μm were calculated.Repeated measurement analysis of variance was performed for comparison of CVI between groups.Results The mean values of CVI in the 750,1500,3000 and 4500μm groups were 0.681±0.003,0.678±0.002,0.677±0.002 and 0.676±0.002,respectively.The difference between the 750μm group and the 4500μm group was 0.005±0.002(P=0.009).The other pairwise comparison results showed no statistically significant difference(P>0.05).Conclusion The CVI is different in healthy eyes with the different distance from macular fovea.