核酸阳性新型冠状病毒感染120例临床特征分析

Clinical characteristics of 120 patients infected with SARS-CoV-2

目的了解新型冠状病毒肺炎(COVID-19)的临床、实验室及影像学特性。方法收集120例确诊为新型冠状病毒感染的病例,并对一般情况、主要临床表现、转归、实验室结果、影像学等进行统计学分析。结果 COVID-19多在中老年发病,性别差距不大,其治疗时间在(14±5)d,病死率7.5%,治愈率33.3%,但重症患者男性较多,且死亡患者年龄较大(中位数为61.5岁)。主要临床症状为发热(75%)、咳嗽(52.5%)、胸闷喘气(14%)、咳痰(7.5%)、乏力(7.5%)等。其实验室结果以白细胞不升、淋巴细胞绝对值降低、嗜酸性粒细胞消失、单核细胞增高及超敏C反应蛋白升高为主,影像学以双肺多发或单发磨玻璃影为主。结论 COVID-19是一种传染性极强的疾病,但其治愈率较高,病死率较低,且为可防、可治的一种疾病。

Objective To investigate the clinical, laboratory and imaging characteristics of COVID-19. Methods A total of 120 cases of SARS-CoV-2 infection were collected and analyzed in general situation, main clinical manifestations, prognosis, laboratory results and imaging findings. Results Most cases of COVID-19 occurred in the middle-aged and elderly, and there was no significant difference between genders. The treatment time was(14±5) days, the mortality was 7.5%, and the cure rate was 33.3%. The severe cases were more often in males, and the dead cases were with older age(median age 61.5 years). The main clinical symptoms were fever(75%), cough(52.5%), shortness of breath(14%), expectoration(7.5%) and weakness(7.5%). The laboratory results showed that the normal white blood cells, the reduced absolute value of lymphocyte, disappeared eosinophil granulocyte, and increased monocytes and high sensitive CRP increased were presented. Conclusion COVID-19 is a highly infectious disease, but its cure rate is high and mortality is low. It is a preventable and treatable disease.