基于时效分析的急诊溶栓临床干预路径应用于急诊溶栓中的效果分析

Effect analysis of emergency thrombolysis clinical intervention pathway based on time-effect analysis in emergency thrombolysis

目的探究基于时效分析的急诊溶栓临床干预路径对急性缺血性卒中患者急诊溶栓治疗的效果。方法选取2017年6月~2018年5月南京医科大学附属南京医院(南京市第一医院)(以下简称“我院”)收治行的病房溶栓的急性缺血性卒中患者58例,将其作为对照组;另选取我院2018年6月~2019年5月收治的行基于时效分析的急诊溶栓临床干预路径的急性缺血性卒中患者58例,将其作为观察组。比较两组时效指标、神经功能及生活能力。结果观察组医嘱下达-CT登记时间、CT检查-溶栓治疗时间及患者入院至静脉溶栓门-针时间(DNT)时间均显著短于对照组,差异有统计学意义(P<0.05)。观察组溶栓治疗7 d后美国国立卫生研究院卒中量表评分显著低于对照组,差异有统计学意义(P<0.05)。观察组患者发病3个月后生活能力良好率显著高于对照组,差异有统计学意义(P<0.05)。结论基于时效分析的急诊溶栓临床干预路径应用于急诊溶栓治疗中可有效缩短DNT时间,改善患者神经功能及生活能力,值得推广。

Objective To explore the effect of emergency thrombolysis clinical intervention pathway based on time-effect analysis on acute ischemic stroke patients.Methods From June 2017 to May 2018,a total of 58 patients with acute ischemic stroke admitted to Nanjing First Hospital.Nanjing Medical University(Nanjing First Hospital)(hereinafter referred to as“our hospital”)for thrombolysis in the ward were selected,as the control group.In addition,a total of 58 patients with acute ischemic stroke admitted to our hospital from June 2018 to May 2019 with emergency thrombolytic clinical intervention pathway based on aging analysis were selected,as an observation group.The aging index,nerve function and living ability of the two groups were compared.Results In terms of doctor's advice issued-CT registration time,CT examination-thrombolytic treatment time,and door-to-needle time(DNT)time from admission to intravenous thrombolytic portal in the observation group were significantly shorter than those in the control group(P<0.05).The national institutes of health stroke scale score of the observation group was significantly lower than that of the control group 7 days after thrombolytic therapy(P<0.05).The rate of good living ability 3 months after the onset of the disease in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of the clinical intervention path of emergency thrombolysis based on the aging analysis in the emergency thrombolysis treatment can effectively shorten DNT time and improve the neurological function and living ability of patients,which is worth promoting.