1Roeleveld DM, Koenders MI. The role of the Thl7 cytokines 1L- 17 and IL-22 in Rheumatoid Arthritis pathogenesis and developments in eytokine immunotherapy[ J/OL]. Cytokine, 2014 [2014-05-12]. http://www, seieneedireet, com/science/article/ pii/S104346661400550X. [ published online ahead of print Nov 20,2014].
2Bettelli E, CarrierY, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T ceils[ J]. Nature, 2006, 441 (7090) :235-238.
3Smolen JS, Landew6 R, Breedveld FC, et at. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs [J]. Ann Rheum Dis, 2010,69(6) :964-975.
4Colin EM, Asmawidjaja PS, van Hamburg JP, et al. 1,25- dihydroxyvitamin D3 modulates Thl7 polarization and interleukin- 22 expression by memory T cells from patients with early rheumatoid arthritis [ J ]. Arthritis Rheum, 2010,62 ( 1 ) : 132- 142.
5Jain M, Attur M, Furer V, et al. Increased Plasma IL-17F Levels in Rheumatoid Arthritis Patients Are Responsive to Methotrexate, Anti-TNF, and T Cell Costimulatory Modulation [ J/OL ]. Inflammation, 2014 [ 2014-05-12 ]. http://link, springer, com/ article/10. 1007% 2Fs10753-014-0020-1. [ published online ahead of print Sep 21,2014].
6Li Y, Jiang L, Zhang S, et al. Methotrexate attenuates the Thl7/ IL-17 levels in peripheral blood mononuclear ceils from healthy individuals and RA patients [ J ]. Rheumatol Int, 2012,32 ( 8 ) : 2415-2422.
7Joosten LA, Radstake TR, Lubberts E, et al. Association ofinterleukin-18 expression with enhanced levels of both interleukin- lbeta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis [ J ]. Arthritis Rheum, 2003,48 (2) :339-347.
8Katz Y, Nadir O, Beer Y. Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a " fine-tuning cytokine" in inflammation processes[ J]. Arthritis Rheum, 2001, 44(9) :2176-2184.
9Xie Q, Huang C, Li J. Interleukin-22 and rheumatoid arthritis: Emerging role in pathogenesis and therapy [ J/OL ]. Autoimmunity, 2014 [ 2014-05-12 ]. http://informahealtheare. com/doi/ahs/10. 3109/08916934. 2014. 959165. [ published online ahead of print Dec 8,2014].
10Zheng Y, Danilenko DM, Valdez P, et al. Interleukin-22, a T(H) 17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis [ J ]. Nature, 2007,445 ( 7128 ) : 648-651.