真性红细胞增多症和原发性血小板增多症与脑血栓形成

Polycythemia vera and essential thrombocytosis and cerebral thrombosis

真性红细胞增多症(polycythemia vera,PV)和原发性血小板增多症(essential thrombocythemia,ET)是最常见的2种骨髓增生性疾病亚型.近年来的研究显示,脑血栓形成是PV和ET的主要并发症之一,与患者转归不良密切相关.此外,PV和ET也会增高脑血栓形成患者的脑血管事件复发风险.文章对PV和ET与脑血栓形成相关性的研究进展进行了综述,以期为PV和ET的临床防治提供依据.

Polycythemia vera(PV)and essential thrombocythemia(ET)are the two most common subtypes of myeloproliferative diseases.Recent studies have shown that cerebral thrombosis is one of the major complications of PV and ET,which is closely related to the poor outcomes of patients.Meanwhile,PV and ET also increase the risk of recurrent cerebrovascular events in patients with cerebral thrombosis.This article reviews the research progress on the correlation between PV and ET and cerebral thrombosis,in order to provide the basis for clinical prevention and treatment of PV and ET.