风药在运动神经元病治疗中应用的理论探讨

Theoretical Exploration on Wind-dispelling Medicine for Treatment of Motor Neuron Disease

运动神经元病的基本病机在于本虚标实,以肝脾肾三脏虚损为本,常以风动为标。风邪在痿证发生中起重要作用,其性主动、易袭阳位的致病特点与运动神经元病临床特征具有一致性。基于风邪致痿理论,运动神经元病治疗中配伍风药可选用黄芪、肉桂、巴戟天助源温息肝风,柴胡、升麻、荷叶升发清阳举陷,牛膝、秦艽、桑寄生活血养血舒筋,钩藤、天麻疏肝解郁散火,桂枝、姜黄、全蝎、地龙、穿山甲辛散搜风通络,蝉蜕、桔梗、威灵仙上行利窍启闭,同时可达到助补不致滋腻、双向通调肠腑之功。不同风药均有其个性专长,善用之可获奇效。

The basic pathogenesis of motor neuron disease is the deficiency in origin and excess in superficiality,of which Liver/spleen/kidney deficiency is the root cause,and stirring wind is the superficial manifestation.Pathogenic wind plays an important role in the development of motor neuron disease which has the similar characteristics of pathogenic wind.Based on the theory of flaccidity syndrome caused by pathogenic wind,the combination of wind-dispelling medicine in the treatment of motor neuron disease can supply source and remove Wind warmly by Huangqi(astragalus),Rougui(Fleshy Cinnamon),Bajitian(morinda),lift Yang from being trapped by Chaihu(bupleurum),Shengma(cimicifuga),Heye(lotus leaf),promote blood circulation and sooth joints by Niuxi(achyranthes),Qinjiao(large gentian),Sangjisheng(mistletoe),relieve depression by open the stagnation of Gan-qi and remove Fire by Gouteng(uncaria),Tianma(gastrodia),disperse Wind and dredge collaterals by Guizhi(cinnamon twig),Jianghuang(turmeric),Quanxie(scorpion),Dilong(earthworm),Chuanshanjia(pangolin scales),open the upward orifice by Chantui(cicada molting),Jiegeng(platycodon),Weilingxian(clematis)and replenish in a non-greasy way and regulate the intestine in both directions simultanously.Different winddispelling medicines have their own personality expertise,and can be used for special effects.