纳米铜簇合成与应用在生物医药领域的研究进展

Advances in the synthesis and applications of coppernanoclusters in biomedicine

纳米铜簇是由几个到几十个原子组成且尺寸接近费米波长的相对稳定聚集体,因其合成方法简单、生物相容性好及独特光、电、磁性质等优点,使其具有广泛的应用前景。本文中,笔者主要介绍了纳米铜簇的合成方法、优良的理化性质和应用进展,重点总结了近年来纳米铜簇在金属离子、生物分子、pH、温度、药物与抗菌等方面分析检测应用以及在化学催化、生物成像等领域的应用进展,以期为拓展铜簇在生物医药等领域的应用奠定基础。

In recent years,copper nanoclusters(Cu NCs)comprising of several to tens of copper atoms have received a great deal of attentions.Taking advantages of their amazing features such as simple preparations,excellent biocompatibility and unique optical,electrical as well as magnetic properties,Cu NCs are very promising materials in wide-field applications.In this review,we introduce the synthesis methods,excellent physicochemical properties and applications of Cu NCs and mainly focus on their applications in biomedicine fields including the detection of metal ions,biomolecule,pH,temperature,chemical catalysis and biological imaging have been reported,in order to expand the application of Cu NCs in biomedicine and other fields.