2020年美国胃肠病学会《慢性胰腺炎临床指南》解读

Interpretation of Clinical Guidelines for Chronic Pancreatitis issued by the American College of Gastroenterology in 2020

慢性胰腺炎(CP)的诊断依据已逐步从临床病理学转变为早期致病机制,新的诊断思路是一种“追根溯源”的方法,关注疑似病人基因和环境的相互作用,从病因入手,更全面地处理并发症,以尽可能改善预后。2020年2月,美国胃肠病学会(ACG)发表了最新的《慢性胰腺炎临床指南》,针对CP诊治过程中的21个临床关键问题提出共识性建议,依次从CP病人的诊断、病因、病史、疼痛管理及胰腺外分泌功能不全(EPI)的处理等多个方面进行探讨,多角度分析并提出临床实用的建议与概念,为临床医生的诊断与治疗CP提供较全面的指导。

The current diagnostic basis of chronic pancreatitis(CP)has gradually shifted from clinical pathology to early pathogenic mechanisms.The emerging diagnostic idea is a tracing to the source method,focusing on the complex genes and environmental interactions of suspected patients.Starting with the cause can deal with complications more comprehensively so as to improve the prognosis.In February 2020,the American College of Gastroenterology(ACG)issued Clinical Guidelines for Chronic Pancreatitis,which provided recommendations on 21 clinical issues in the diagnosis and treatment of CP,discussed the diagnosis,etiology,medical history,pain management and exocrine pancreatic insufficiency treatment of CP patients in turn,analyzed from multiple perspectives and put forward practical suggestions and concepts for clinical practice,so as to provide comprehensive guidance for clinicians.