摘要
目的:详述以1~3倍人均GDP作为药物经济学评价阈值的历史渊源及应用现状。方法:基于文献溯源和概念分析的方法对已有文献进行梳理总结。结果:1~3倍人均GDP阈值最初是以可避免的伤残调整生命年作为结果指标的平均成本效果比的阈值,后来学者逐渐以质量调整生命年替代伤残调整生命年作为结果指标,同时挪用其为增量成本效果比的阈值。结论:以1~3倍人均GDP作为药物经济学评价阈值无可负担性保证;该阈值假设条件不合理;同时,使用1~3倍GDP作为阈值时评价结果不具有外推性。
Objective:It elaborates the historical pass and the empirical status of 1~3 GDP thresholds.Methods:Literature tracing and conceptual analysis are to summarize the literature.Results:The threshold is set for average cost per effectiveness,where averted Disability Adjusted Life Year(DALY)is applied as effectiveness measure. Gradually,researchers adopt Quality Adjusted Life Year(QALY) instead of DALY as health-related outcome;meanwhile 1~3 GDP thresholds is taken as threshold of incremental cost-effectiveness ratio.Conclusion:There is no budget limit while applying 1~3 GDP thresholds;the underlying assumption is the not reasonable;meanwhile,there is no extrapolation for the evaluation result while applying 1~3 GDP thresholds.
作者
叶子平
马佳
刘抚瑶
王臣
周紫阳
孙利华
YE Ziping;MA Jia;LIU Fu-yao(College of business administration,Shenyang Pharmaceutical University,Shenyang,110016,China)
出处
《中国卫生经济》
北大核心
2020年第5期72-75,共4页
Chinese Health Economics
基金
辽宁省教育厅人文社会科学研究重点攻关项目(2019WZD01)。