儿童侵袭性肺炎链球菌疾病及其致病菌株研究进展

Updates on invasive pneumococcal disease′s in children and their pathogenic strains

肺炎链球菌是儿童常见的感染性病原,可以引起侵袭性和非侵袭性疾病,而侵袭性疾病造成的负担和后果尤为严重。现阐述侵袭性肺炎链球菌疾病的流行病学、疾病分布及其菌株变化的最近进展,为疫苗设计、免疫策略的选择及临床诊治提供参考。

Streptococcus pneumoniae is a common pathogen of infections in children,and can cause invasive and non-invasive diseases.The invasive diseases cause extremely heavy burden and particularly serious consequences to patients.In this article,the recent progress in the epidemiology,disease distribution,and strain changes of invasive pneumococcal diseases was reviewed,which provided reference for vaccine design,immunization program implementation and clinical treatment.