动态血糖监测在门冬胰岛素30皮下注射治疗2型糖尿病患者中的应用分析

Analysis of the application of dynamic blood glucose monitoring in the treatment of type 2 diabetic patients by subcutaneous injection of aspartic insulin 30

目的研究在接受门冬胰岛素30皮下注射治疗的2型糖尿病患者中进行动态血糖监测的效果。方法选择2017年8月至2018年12月本院收治的126例2型糖尿病患者作为研究对象,按照入院顺序分为观察组与对照组,各63例,两组患者均接受门冬胰岛素30皮下注射治疗,观察组另外行动态血糖监测,对照组行定期血糖监测,比较两组治疗效果。结果观察组治疗7 d后空腹血糖以及餐后0.5 h、1 h、2 h血糖水平均低于对照组(t=16.505、4.971、6.384、6.423,P<0.05);观察组治疗结束后Homa-IR、Homa-β、FINS、空腹及2 h C肽结果均优于对照组(t=6.437、11.358、3.428、5.169、5.204,P<0.05);观察组低血糖发生率为4.76%,低于对照组的17.46%(χ^2=5.143,P<0.05)。结论对接受门冬胰岛素30皮下注射治疗的2型糖尿病患者实施动态血糖监测能够更有效控制血糖,改善胰岛素功能,减少低血糖的发生,有推广价值。

Objective To study the effect of dynamic blood glucose monitoring in patients with type 2 diabetes mellitus(T2DM) who received insulin aspart 30 subcutaneous injection. Methods 126 patients with type 2 diabetes admitted to our hospital from August 2017 to December 2018 were divided into observation group and control group according to the order of admission. There were 63 patients in the two groups, both of whom received insulin aspartame 30 subcutaneous injection. In addition, the observation group received blood glucose monitoring in action, while the control group received regular blood glucose monitoring to compare the treatment effect of the two groups. Results The fasting blood glucose and 0.5 h,1 h and 2 h postprandial blood glucose in the observation group were lower than those in the control group(t=16.505, 4.971, 6.384 and 6.423, P<0.05).The results of HOMA IR, HOMA β, FINS, fasting and 2 h C peptide in the observation group were better than those in the control group(t=6.437,11.358, 3.428, 5.169 and 5.204, P<0.05). The incidence of hypoglycemia in the observation group was 4.76%, lower than that in the control group17.46%(χ^2=5.143, P<0.05). Conclusion The dynamic blood glucose monitoring of type 2 diabetic patients who received insulin 30 subcutaneous injection can effectively control blood glucose, improve insulin function and reduce the incidence of hypoglycemia, which is worth popularizing.