经直肠超声弹性成像技术对前列腺周围区癌灶的敏感性分析

Sensitivity analysis of transrectal ultrasound elastography in cancerous areas around the prostate

目的:回顾性分析经直肠超声弹性成像技术对前列腺周围区癌灶的敏感性。方法:选取2015年4月—2019年4月医院收治的疑似前列腺癌患者236例,分别采用经直肠超声成像和经直肠超声压力弹性成像检查方法,以病理检查结果为金标准,比较两种检查方法的敏感性。结果:所选236例患者中,病理确诊前列腺癌患者124例,经直肠超声压力弹性成像诊断96例,诊断准确率为77.42%;病理检查发现前列腺癌灶214个,经直肠超声压力弹性成像发现146个,诊断准确率为68.22%。在前列腺周围区癌灶的诊断中,经直肠超声成像的敏感度为52.80%、特异度为71.90%,经直肠超声压力弹性成像的敏感度为73.60%、特异度为72.70%,二者敏感度有显著差异(P<0.05)。在前列腺中央区及移行区癌灶的诊断中,经直肠超声成像的敏感度为57.10%、特异度为70.70%,经直肠超声压力弹性成像的敏感度为57.10%、特异度为71.30%,二者敏感度无显著差异(P>0.05)。结论:在前列腺癌灶的诊断当中,结合使用经直肠超声压力弹性成像检查技术能够取得较高的诊断准确率,同时敏感性及特异性较高,故其具有较高的临床应用价值。

Objective To retrospectively analyze the sensitivity of transrectal ultrasound elastography to cancerous lesions around the prostate.Method Choose the 236 suspected prostate cancer patients,treated through transrectal ultrasound imaging and transrectal ultrasound pressure elastrography in our hospital from April,2015 to April 2019,and compare the sensitivity of the inspection methods,based on the gold standard of pathological examination results.Results Of the 236 suspected cases,124 were pathologically confirmed as prostate cancer,while 96 were confirmed as prostate cancer through transrectal ultrasound pressure elastography diagnosis.The diagnostic accuracy is 77.42%.Two hundred and fourteen prostate cancer neoplastci foci were revealed through pathological examination while 146 through transrectal ultrasound pressure elastography diagnosis.The diagnostic accuracy is 68.22%.In the diagnosis of cancerous areas around the prostate,the sensitivity of transrectal ultrasound imaging is 52.80%and the specificity is 71.90%;the sensitivity of transrectal ultrasound pressure elastography is 73.60%and the specificity is 72.70%.There exist significant differences between the two kinds of sensitivity(P﹤0.05).In the diagnosis of cancer in the central and transitional prostate regions,the sensitivity of transrectal ultrasound is 57.10%and the specificity is 70.70%,while the sensitivity of transrectal ultrasound pressure is 57.10%and the specificity is 71.30%.There is no significant difference in sensitivity between the two(P﹥0.05).Conclusion In the diagnosis of prostate cancer,the combined use of transrectal ultrasound pressure elastography can achieve a higher diagnostic accuracy rate and higher sensitivity and specificity,so it has higher clinical application value.