泻金通腑汤联合西药治疗胸腹联合伤术后临床研究

Clinical Study on Xiejin Tongfu Tang Combined with Western Medicine after Surgery of Thoraco-abdominal Injuries

目的:观察泻金通腑汤联合西药在胸腹联合伤术后恢复中的治疗效果。方法:将胸腹联合伤患者92例随机分为对照组与治疗组,每组各46例,2组均行胸腹部外科手术,对照组术后给予常规西药治疗,治疗组在对照组的基础上加用泻金通腑汤治疗;观察比较2组术后胃肠功能恢复情况,包括肛门排气时间、腹胀缓解时间与肠鸣音恢复时间;比较2组治疗前后C-反应蛋白(CRP)、白细胞(WBC)与白细胞介素-6(IL-6)水平变化;比较2组术后并发症发生情况。结果:治疗后,治疗组肛门排气、腹胀缓解、肠鸣音恢复时间均明显短于对照组,差异有统计学意义(P<0.05)。治疗后,2组患者CRP、WBC、IL-6水平均较治疗前明显降低(P<0.05),且治疗组上述指标均明显低于对照组(P<0.05)。并发症总发生率治疗组为15.22%,对照组为36.96%,2组比较,差异有统计学意义(P<0.05)。结论:泻金通腑汤应用于胸腹部联合伤术后,可明显加速胃肠功能恢复,减少炎症因子释放及并发症发生,值得临床推广应用。

Objective:To observe the curative effect of Xiejin Tongfu tang combined with western medicine on the postoperative recovery of thoraco-abdominal injuries.Methods:A total of 92 cases of patients with thoraco-abdominal injuries were randomly divided into the control group and the treatment group,46 cases in each group.Both groups were given thoracoabdominal surgery.After surgery,the control group was treated with routine western medicine,and the observation group was additionally given Xiejin Tongfu tang based on the treatment of the control group.The postoperative recovery of gastrointestinal function including the anal exhaust time,the remission time of abdominal distention and the recovery time of bowel sounds in the two groups were observed and compared.The changes in the levels of C-reactive protein(CRP),white blood cells(WBC)and interleukin-6(IL-6)before and after treatment as well as the incidence of postoperative complications were compared between the two groups.Results:After treatment,the anal exhaust time,the remission time of abdominal distention and the recovery time of bowel sounds in the treatment group were significantly shorter than those in the control group,the difference being significant(P<0.05).After treatment,the levels of CRP,WBC and IL-6 in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the above levels in the treatment group were significantly lower than those in the control group(P<0.05).The total incidence of complications was 15.22%in the treatment group,and 36.96%in the control group,the difference being significant(P<0.05).Conclusion:The application of Xiejin Tongfu tang in the postoperative recovery of thoraco-abdominal injuries can significantly accelerate the recovery of gastrointestinal function,and reduce the release of inflammatory factors and the incidence of complications,which is worthy of clinical promotion and application.