慢性肝病肝纤维化程度与周围血细胞计数的相关性分析

Analysis of the Correlation between the Degree of Liver Fibrosis and Peripheral Blood Cell Count in Chronic Liver Disease

目的探讨慢性肝病肝纤维化程度与周围血细胞计数的相关性。方法在医院2016年9月至2018年9月诊治的慢性肝病患者中选取200例作研究对象,并按肝纤维化分期予以分组:S0组、S1组、S2组、S3组、S4组,各40例,并选取肝硬化患者40例,设为肝硬化组;对上述六组患者进行周围血细胞计数检测,并就6组血细胞计数指标差异进行统计学分析。结果从S0组开始直至肝硬化组,外周血细胞计数四项数据呈现下降趋势,为便于统计组间差异有无统计学意义进行组别合并,其中S0~S2组外周血细胞计数指标水平最高高于S3~S4组(t=6.111、12.734、4.611、5.642,均P=0.000),而S3~S4组高于肝硬化组(t=16.612、2.412、10.479、4.492,P=0.000、0.009、0.000、0.000)。结论慢性肝病肝纤维化程度与周围血细胞计数之间存在相关性,可借鉴。

Objective To investigate the correlation between the degree of liver fibrosis and peripheral blood cell count in chronic liver disease.Methods From September 2016 to September 2018,200 patients with chronic liver diseases were selected and divided into four groups according to the stages of liver fibrosis:S0 group,S1 group,S2 group,S3 group,S4 group,40 patients with liver cirrhosis,and 40 patients with liver cirrhosis were selected as liver cirrhosis group.Statistical analysis.Result From S0 group to cirrhosis group,the four data of peripheral blood cell count showed a downward trend.There was no significant difference between groups for statistical purposes.The highest level of peripheral blood cell count in S0-S2 group was higher than that in S3-S4 group(t=6.111,12.734,4.611,5.642,P=0.000),while that in S3-S4 group was higher than that in cirrhosis group(t=16.612,2.412,10.479,4.492,P=0.000,0.009,0.000,0.000).Conclusion There is a correlation between the degree of liver fibrosis and peripheral blood cell count in chronic liver disease.It is worth learning.