UTAMB及咪达唑仑-右美托咪定在腹膜透析置管术中的应用

APPLICATION OF UTAMB AND MIDAZOLAM-DEXMEDETOMIDINE IN PD CATHETERIZATION

目的探讨PD置管术的麻醉方法。方法选取90例ESRD需行PD置管术患者,将其随机分成观察组(40例)、对照组一组(29例)和对照组二组(21例)。观察组行UTAMB,术中伍用咪达唑仑-右美托咪定持续镇静;对照组一组仅行UTAMB;对照组二组用局麻,术中给予一定量的咪达唑仑-右美托咪定。比较三组疼痛指数、MAP、HR、医师舒适度等。结果除T1外,三组其他时间点MAP比较均以对照一组最高(q=4.08~17.12,P<0.05);观察组镇痛效果、医师舒适度的优良率高于其他两组(χ^2=20.46,P<0.01)。结论UTAMB伍用咪达唑仑-右美托咪定对PD置管术安全,更有效。

Objective To explore the anesthesia method of PD catheterization.Methods Ninety patients with ESRD who needed PD catheterization were randomly divided into observation group(40 cases),control group 1(29 cases),and control group 2(21 cases).The observation group received UTAMB,and midazolam-dexmedetomidine was used for continuous sedation during the operation.Control group 1 received UTAMB only,and control group 2 received local anesthesia Metomidine.The pain index,MAP,HR,and physician comfort level of the three groups were compared.Results Except T1,the MAP comparison of the three groups at other time points was the highest in control group 1(q=4.08-17.12,P<0.05).The analgesic effect and the excellent rate of physician comfort in the observation group were higher than those in the other two groups(χ^2=20.46,P<0.01).Conclusion UTAMB combined with midazolam-dexmedetomidine is safe and more effective for PD catheterization.