普拉克索片联合美多芭治疗帕金森病的效果观察

THE EFFECT OF PRAMIPEXOLE COMBINED WITH MEDOBA ON PARKINSON'S DISEASE

目的探讨帕金森病的治疗方法。方法选取250例帕金森病患者,将其随机分为实验组和对照组,各125例。对照组给予美多芭治疗,实验组加用普拉克索片治疗。采用综合量表评估两组相关指标改善情况,比较两组临床症状缓解时间及疗效。结果实验组综合量表评分改善情况优于对照组(t=4.97~32.78,P<0.01);总有效率高于对照组(χ^2=7.09,P=0.008);临床症状缓解时间明显短于对照组(t=10.96~24.01,P<0.01)。结论普拉克索联合美多芭能有效提高帕金森病的疗效。

Objective To explore the treatment of Parkinson's disease.Methods 250 patients with Parkinson's disease were selected and randomly divided into experimental group and control group,125 cases each.The control group was treated with Medopa,and the experimental group was treated with pramipexole tablets.The comprehensive scale was used to evaluate the improvement of the relevant indicators of the two groups,and the clinical symptom relief time and efficacy were compared between the two groups.Results The improvement of the comprehensive scale score of the experimental group was better than that of the control group(t=4.97~32.78,P<0.01).The total effective rate was higher than that of the control group(χ^2=7.09,P=0.008).The clinical symptom relief time was significantly shorter than the control group(t=10.96~24.01,P<0.01).Conclusion Praxsol combined with Medopa can efficiently improve the curative effect of Parkinson's disease.