序贯呼吸机对重症肺炎合并呼吸衰竭患者血清指标和氧合功能的临床价值

Clinical value of sequential ventilator on serum indexes and oxygenation function in patients with severe pneumonia complicated with respiratory failure

目的探讨序贯呼吸机对重症肺炎合并呼吸衰竭患者血清指标和氧合功能的治疗效果。方法选取本院2015年2月~2019年2月诊治的重症肺炎合并呼吸衰竭患者80例,采用随机数字表法分为两组,对照组患者40例实施常规通气治疗,观察组患者40例实施序贯呼吸机辅助通气治疗,于治疗前后行血清学指标检测和氧合功能评定。比较两组患者的治疗效果和不良反应。结果两组患者治疗后前白蛋白、白蛋白、动脉血氧分压、血氧饱和度较治疗前增加(P<0.05)。两组患者治疗后动脉血二氧化碳分压较治疗前降低(P<0.05)。观察组患者治疗后前白蛋白、白蛋白、动脉血氧分压、血氧饱和度高于对照组(P<0.05)。观察组患者治疗后动脉血二氧化碳分压低于对照组(P<0.05)。观察组患者总有效率高于对照组(P<0.05)。观察组患者机械通气时间、住院时间短于对照组(P<0.05)。观察组患者不良反应发生率低于对照组(P<0.05)。结论序贯呼吸机可显著改善重症肺炎合并呼吸衰竭患者的血清指标和氧合功能,还可缩短治疗时间并提高疗效。

Objective To investigate the therapeutic effects of sequential ventilator on serum indexes and oxygenation function in patients with severe pneumonia complicated with respiratory failure.Methods 80 patients with severe pneumonia complicated with respiratory failure diagnosed and treated in our hospital from February 2015 to February 2019 were selected,and were divided into two groups by using the random number table method.40 patients in the control group were treated with routine ventilation,while 40 patients in the observation group were treated with sequential ventilator assisted ventilation.Serological indexes were tested and oxygenation function was evaluated before and after treatment.The therapeutic effect and adverse reactions were compared between the two groups of patients.Results After treatment,the prealbumin,albumin,arterial partial pressure of oxygen,and oxygen saturation in the two groups of patients were higher than those before treatment(P<0.05).After treatment,the arterial partial pressure of carbon dioxide in the two groups of patients was lower than that before treatment(P<0.05).After treatment,the prealbumin,albumin,arterial partial pressure of oxygen,and oxygen saturation of patients in the observation group were higher than those in the control group(P<0.05).After treatment,the arterial partial pressure of carbon dioxide of patients in the observation group was lower than that in the control group(P<0.05).The overall response rate of patients in the observation group was higher than that in the control group(P<0.05).The duration of mechanical ventilation and hospitalization of patients in the observation group was shorter than that in the control group(P<0.05).The incidence of adverse reactions of patients in the observation group was lower than that in the control group(P<0.05).Conclusion Sequential ventilator can significantly improve the serum indexes and oxygenation function of patients with severe pneumonia complicated with respiratory failure,shorten the treatment time and improve the efficacy.