阻塞性睡眠呼吸暂停与脑卒中的相互关系

The bidirectional interaction between obstructive sleep apnea and stroke

阻塞性睡眠呼吸暂停(OSA)有可能是脑卒中发作或复发的独立危险因素;脑卒中后可继发睡眠呼吸障碍,主要表现为OSA,也可使原有的OSA进一步加重,进而显著增加脑卒中的致残率和病死率。相关此类睡眠疾病与脑卒中之间相互关系的研究始于19世纪,近30年的多项研究指出OSA与脑卒中之间存在着双向联系。本文拟对OSA和脑卒中之间相互关系进行综述,旨在提高临床医师对其的认识,并为临床及相关研究提供新的思路。

The relationship between obstructive sleep apnea(OSA)and stroke has been the subject of many studies.On the one hand,OSA,as a modifiable risk factor,increases the risk of stroke.On the other hand,stroke could potentially disrupt sleep networks and presents with sleep-disordered breathing mainly including OSA,which might increase stroke recurrence and mortality.In this review,we discusses the bidirectional interaction between OSA and stroke.