海拔4000米以上超高原地区幕上高血压脑出血特点分析

Characterization of Patients with Supratentorial Hypertensive Intracerebral Hemorrhage in the Tibetan Plateau over an Altitude of 4000 meters

目的研究海拔4000米以上超高原地区幕上高血压脑出血患者出血特点。方法选取阿里地区人民医院2017年1月至2018年9月共68例幕上脑出血患者,采集临床资料并测量出血量,应用简单线性相关分析法分析患者性别、年龄、民族、发病时间、入院收缩压、舒张压、血红蛋白、血清三酰甘油及胆固醇化验值等因素与出血量的相关性,并根据CT结果分为基底节区组(33例)和脑叶组(35例),采用t检验或χ^2检验分析基底节区组与脑叶组出血不同特点。结果研究组68例患者性别、年龄、民族、发病时间、入院时收缩压、舒张压、血红蛋白、血清三酰甘油及胆固醇化验值与出血量均无明确相关性(P>0.05);基底节区组收缩压和舒张压均高于脑叶组[(184.9±28.5)mmHg(1 mmHg=0.133 kPa)vs(164.6±24.4)mmHg,(113.0±18.1)mmHg vs(103.0±18.4)mmHg],差异均具有统计学意义(t=0.499、0.486;P=0.002、0.033)。结论超高原脑出血患者出血量相关因素尚不明确,出血位于基底节区与位于脑叶患者的收缩压和舒张压具有不同特点。

Objective To characterize the patients with supratentorial hypertensive intracerebral hemorrhage(ICH)in the Tibetan Plateau over an altitude of 4000 meters.Methods A total of 68 cases with supratentorial hypertensive ICH were retrospectively included in Ali Regional People’s Hospital from January 2017 to September 2018.The clinical and laboratory data were collected.A simple linear correlation analysis was applied to analyze the correlation between the amount of bleeding and sex,age,nationality,time from onset,systolic blood pressure(SBP),diastolic blood pressure(DBP),hemoglobin(Hb),serum triglyceride(TG),and cholesterol.According to computed tomography(CT)findings,68 cases were divided into the basal ganglia ICH group(33 cases)and the lobar ICH group(35 cases).The characteristics between two groups were analyzed using t-test or χ^2 test.Results The data of sex,age,nationality,time from onset,SBP,DBP,Hb,TG,and cholesterol of 68 cases on admission did not show any definitive correlation with the hematoma volumes(P>0.05).The SBP and DBP of patients in the basal ganglia ICH group were significantly higher than that in the lobar ICH group,respectively[(184.9±28.5)mmHg vs(164.6±24.4)mmHg;(113.0±18.1)mmHg vs(103.0±18.4)mmHg](t=0.499,0.486;P=0.002,0.033).Conclusion The relevant factors of hematoma volumes in patients with ICH in plateau area were not yet clear.Diastolic and systolic blood pressure of patients in the basal ganglia ICH group was higher than that in those in lobar ICH group.