吡咯生物碱相关肝窦阻塞综合征1例报道

Pyrrolidine alkaloid-related hepatic sinusoidal obstruction syndrome: one case report

肝窦阻塞综合征(hepatic sinusoidal obstruction syndrome,HSOS)是一种少见的肝血管疾病。国内报道大多因服用含有吡咯生物碱(pyrrolidine alkaloid,PA)的中草药所致,以土三七为代表。该病与布加综合征(Budd-Chiari syndrome,BCS)临床表现极其相似,且临床医师对该病认识不足,易误诊为BCS。本文对1例险些误诊为BCS的HSOS患者的临床资料进行分析,以提高临床医师对该病的认识。

Hepatic sinusoidal obstruction syndrome(HSOS) is a rare hepatic vascular disease. Most of the reports in China are due to the use of Chinese herbal medicine containing pyrrolidine alkaloid, represented by Tusanqi. The clinical manifestations of the disease are very similar to those of Budd-Chiari syndrome(BCS), and clinicians are not well aware of the disease. So it is easy to be misdiagnosed as BCS. This paper analyzed the clinical data of one patient with HSOS who was almost misdiagnosed as BCS in order to improve the clinician’s understanding of the disease.