参苓白术散加减联合化疗治疗中晚期胃癌的临床效果

Clinical effect of addition and subtraction of Shenling Baizhu powder combined with chemotherapy in the treatment of advanced gastric cancer

目的探讨参苓白术散加减联合化疗治疗中晚期胃癌的临床效果。方法将100例中晚期胃癌患者根据治疗方案不同分为观察组(50例,参苓白术散加减联合化疗)与对照组(50例,单纯化疗)。比较两组的治疗效果。结果治疗后,两组的TNF-α、IL-6水平均降低,CD4+/CD8+、Kamofaky评分均升高,且观察组优于对照组(P<0.05)。观察组的治疗总有效率高于对照组(P<0.05)。随访3、6个月后,观察组的生存率均高于对照组(P<0.05)。结论参苓白术散加减联合化疗治疗中晚期胃癌患者效果显著,可提高患者生存质量。

Objective To explore the clinical effect of addition and subtraction of Shenling Baizhu powder combined with chemotherapy in the treatment of advanced gastric cancer.Methods A total of 100 patients with advanced gastric cancer were divided into observation group(50 cases,addition and subtraction of Shenling Baizhu powder combined with chemotherapy)and control group(50 cases,simple chemotherapy)according to the different treatment schemes.The therapeutic effects of the two groups were compared.Results After treatment,the levels of TNF-αand IL-6 in the two groups decreased,the CD4+/CD8+and Kamofaky score increased,and those in the observation group were better than the control group(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After 3,6 months of follow-up,the survival rate in the observation group were higher than those in the control group(P<0.05).Conclusion Addition and subtraction of Shenling Baizhu powder combined with chemotherapy has a significant effect in the treatment of advanced gastric cancer,which can improve the quality of life of patients.