头孢哌酮钠舒巴坦钠结合胸腺五肽治疗糖尿病并肺部感染老年患者效果观察

Effects of Cefoperazone Sodium and Sulbactam Sodium Combined with Thymopentapeptide on Elderly Patients with Diabetes and Lung Infection

目的:观察头孢哌酮钠舒巴坦钠结合胸腺五肽治疗糖尿病并肺部感染老年患者效果。方法:选取2018年5月至2019年5月收治的88例糖尿病合并肺部感染老年患者,随机分为观察组和对照组;观察组患者使用头孢哌酮钠舒巴坦钠结合胸腺五肽进行治疗,对照组患者仅进行头孢哌酮钠舒巴坦钠治疗;比较两组患者的临床疗效、临床症状缓解时间、治疗前后炎性指标水平、不良发应发生情况。结果:观察组患者的临床疗效总有效率为97.73%,高于对照组的79.55%(P<0.05);观察组患者的咳嗽咳痰缓解时间、肺部啰音消失时间、肺部阴影消失时间、退热时间、血糖恢复时间均较对照组缩短(P<0.05);治疗前两组患者的CRP、IL-6指标水平差异无统计学意义(P>0.05),治疗后观察组患者的CRP、IL-6指标水平下降高于对照组(P<0.05);观察组患者的不良反应发生率较对照组低(P<0.05)。结论:头孢哌酮钠舒巴坦钠结合胸腺五肽治疗糖尿病并肺部感染老年患者可提高临床疗效,缩短临床症状缓解时间,降低不良反应发生率及机体炎性水平,促进患者恢复,值得推广。

Objective:To explore the effect of cefoperazone sodium and sulbactam sodium combined with thymopentin in the treatment of elderly patients with diabetes and pulmonary infection.Methods:88 elderly patients with diabetes and pulmonary infection treated from May 2018 to May 2019 were randomly selected.They were divided into observation group and control group.The observation group was given cefoperazone sodium and sulbactam sodium in combination with thymopentin.The control group was given only Cefoperazone Sodium Sulbactam Sodium.The clinical efficacy,clinical symptom relief time,inflammatory index levels before and after treatment were compared between the two groups.Occurrence of adverse symptoms.Results:The total effective rate of clinical efficacy in the observation group was 97.73%compared with 79.55%in the control group.The time of cough and sputum remission,the disappearance of lung rales,the disappearance of lung shadows,the time of fever reduction,and the time of blood glucose recovery were significantly shorter than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the levels of CRP and IL-6 in the two groups before treatment(P>0.05).After treatment,the CRP and IL-6 in the two groups were not significantly different.The levels of indicators decreased significantly,and the levels of CRP and IL-6 in the observation group decreased more significantly.The differences were statistically significant(P<0.05).The incidence rate of 4.54%was significantly lower than that of 18.18%in the control group,and the difference was statistically significant(P<0.05).Conclusion:Cefoperazone sodium and sulbactam sodium combined with thymopentin can significantly improve clinical efficacy in elderly patients with diabetes and lung infection,shorten the time to relieve clinical symptoms,reduce the incidence of adverse reactions,reduce the body's inflammatory level,and promote patient recovery,which is recommended to promote clinically.