化瘀散浊法对女性甲状腺结节瘀浊交阻证的治疗效果

Therapeutic Effect of Resolving Blood Stasis and Dispersing Turbid Method on Female Thyroid Nodules with Blood Stasis and Turbid Syndrome

目的探讨化瘀散浊法对女性甲状腺结节瘀浊交阻证的治疗效果。方法选择2017年1月-2018年1月医院接诊的甲状腺结节女性患者78例,按照随机数字的方法将全部患者分对照组(n=39)和治疗组(n=39),对照组使用常规西医治疗方案,治疗组在对照组基础上使用化瘀散浊法。对两组治疗前后的血清促甲状腺激素水平,甲状腺结节最大直径,血清维生素D水平进行对比。对两组治疗效果对比。对两组在治疗过程中的不良反应情况进行对比。结果治疗后,两组的血清促甲状腺激素水平,甲状腺结节最大直径均降低,血清维生素D水平均增高(t=4.275,2.666,-3.506,3.147,8.626,-5.759,P<0.05),在治疗后的组间比较中,血清促甲状腺激素水平和甲状腺结节最大直径为对照组高于治疗组,血清维生素D水平为对照组低于治疗组(t=2.225,5.580,-2.245,P<0.05),治疗组的治疗效果优于对照组(Z=-3.898,P<0.05),两组的多汗,腹泻,体质量下降,失眠,烦躁发生率数据差异均不具有统计学意义(χ^2=0.513,0.000,0.000,0.264,0.264,P>0.05)。结论使用化瘀散浊法对女性甲状腺结节瘀浊交阻证的患者进行治疗,可以显著改善患者的各项病理指标,提高治疗效果,安全性良好,值得推广。

Objective To explore the therapeutic effect of resolving blood stasis and dispersing turbid method on female thyroid nodules with blood stasis and turbid syndrome. Methods Seventy-eight female patients with thyroid nodules admitted to our hospital between January 2017 and January 2018 were divided into control group(n=39) and treatment group(n=39) according to random number method. The control group was treated with a conventional Western medicine treatment, and the treatment group was treated with resolving blood stasis and dispersing turbid method on the basis of the control group. Serum thyroid stimulating hormone levels, maximum thyroid nodules diameter and serum vitamin D levels were compared between the two groups. We compared the effects of the two groups and the adverse reactions during treatment. Results After treatment, serum thyroid stimulating hormone levels and maximum diameter of thyroid nodules were decreased, and serum vitamin D levels were increased(t=4.275, 2.666,-3.506, 3.147, 8.626,-5.759, P<0.05). In the comparison between groups after treatment, the serum thyroid stimulating hormone level and the maximum diameter of thyroid nodules were higher in the control group than those in the treatment group, and the serum vitamin D level was lower in the control group than that in the treatment group(t=2.225, 5.580,-2.245, P<0.05). The treatment effect of the treatment group was better than that of the control group(Z=-3.898, P<0.05). There were no statistically significant differences in data on sweating, diarrhea, weight loss, insomnia or irritability between the two groups(χ^2=0.513, 0.000, 0.000, 0.264, 0.264, P>0.05). Conclusion The treatment of women with thyroid nodules and opacity syndrome by using resolving blood stasis and dispersing turbid method can significantly improve the pathological indicators of patients and the therapeutic effect, and has good safety. It is worthy of promoting.