知信行一体化护理对呼吸衰竭患者炎症因子表达水平和呼吸功能的影响

Effect of integrated nursing mode of knowledge attitude practice on expression of inflammatory factors and respiratory function in patients with respiratory failure

目的探究知信行一体化护理(KAP)对呼吸衰竭患者的炎症因子表达水平和呼吸功能的影响。方法选取接受诊治的呼吸衰竭126例患者,随机分为护理组和对照组,各63例。对照组行常规护理,护理组行KAP护理模式。比较干预后两组炎症因子表达水平和呼吸功能。结果护理组重度焦虑程度和重度抑郁程度低于对照组,差异均有统计学意义(均P<0.05)。治疗前,两组患者动脉氧分压(PaO2)、吸入氧气分率(FiO2)及氧合指数(OI)值比较差异无统计学意义(P>0.05),治疗后,护理组患者PaO2、FiO2、OI改善程度显著优于对照组,差异无统计学意义(P>0.05)。两组患者治疗前CRP、IL-6和TNF-α检测比较差异无统计学意义(P>0.05),治疗后,两组炎性指标均降低,护理组炎症指标改善程度显著优于对照组,差异均有统计学意义(P<0.05)。治疗后,护理组患者生活质量显著高于对照组,差异有统计学意义(P<0.05)。结论KAP护理改善呼吸衰竭患者的焦虑和抑郁情绪,对降低炎症指标具有积极作用,提高患者生活质量。

Objective To explore the effect of the integrated nursing mode of knowledge attitude practice on the expression of inflammatory factors and respiratory function in patients with respiratory failure.Methods A total of 126 patients with respiratory failure were randomly divided into the nursing group and the control group,63 cases of each group.The control group received routine nursing,and the nursing group received KAP nursing mode.The expression levels of inflammatory factors and respiratory function of the two groups after intervention were compared.Results The severity of anxiety and severity of major depression in the nursing group were lower than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in PaO2,FiO2 and OI levels between the two groups,and the difference was not statistically significant(P>0.05).After treatment,the improvement of PaO2,FiO2 and OI levels in the nursing group was better than those in the control group,but there was no statistical significance(P>0.05).There was no significant difference in the detection of CRP,IL-6 and TNF-αlevels between the two groups(P>0.05).After treatment,the inflammatory indexes of the two groups were decreased.The improvement of the inflammation indexes in the nursing group was significant higher than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the overall quality of life of the nursing group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusions The nursing mode of knowledge attitude practice can effectively ameliorate the anxiety and depression of patients with respiratory failure.It also has a positive effect on reducing inflammation index and improving respiratory function,and improve the quality of life of patients,which is conducive to the treatment and rehabilitation of patients.