前哨淋巴结活检联合腋窝淋巴结清扫术在乳腺癌患者中的应用效果

Sentinel Lymph Node Biopsy Combined with Axillary Lymph Node Dissection in Breast Cancer Patients

目的探讨前哨淋巴结活检联合腋窝淋巴结清扫术治疗乳腺癌患者的效果。方法回顾性分析2017年2月至2018年6月于福建省漳州市中医院就诊的84例乳腺癌患者的临床资料,根据淋巴处理方案的不同分为对照组和试验组,每组42例。对照组采用腋窝淋巴结清扫术,试验组采用前哨淋巴结活检联合腋窝淋巴结清扫术,比较两组的手术相关指标、术后1年简明健康状况量表(SF-36)评分及术后并发症发生情况。结果试验组手术时间长于对照组,但引流管拔除时间短于对照组,术中出血量及引流量均少于对照组,差异有统计学意义(P<0.05)。术后1年,试验组SF-36评分高于对照组,差异有统计学意义(P<0.05)。试验组术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论前哨淋巴结活检联合腋窝淋巴结清扫术治疗乳腺癌患者有利于减少术后并发症的发生,提升患者的生命质量。

Objective To investigate the clinical effect of sentinel lymph node biopsy combined with axillary lymph node dissection in the treatment of breast cancer.Methods The clinical data of 84 breast cancer patients who were diagnosed and treated in Zhangzhou Hospital of Traditional Chinese Medicine from February 2017 to June 2018 were analyzed retrospectively.They were divided into the control group and the experimental group according to the different treatment schemes,42 cases in each group.The control group were treated with axillary lymph node dissection,and the experimental group were treated with sentinel lymph node biopsy combination with axillary lymph node dissection.The operation related indexes of the two groups were observed and compared After one year later,the quality of life and postoperative complications of the two groups were analyzed.Results The operation time of the experimental group was longer than that of the control group,but the drainage tube extraction time was shorter than that of the control group,and the intraoperative blood loss and drainage volume were less than that of the control group,with statistically significant differences(P<0.05).One year after the operation,the sf-36 score of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The sentinel lymph node biopsy combined with axillary lymph node dissection can reduce complications and improve the quality of life of breast cancer patients.