类风湿关节炎应用艾拉莫德联合甲氨蝶呤治疗的有效性分析

Effectiveness of Elamode Combined with Methotrexate in the Treatment of Rheumatoid Arthritis

目的探究类风湿关节炎应用艾拉莫德联合甲氨蝶呤治疗的有效性。方法选取2017年12月至2018年12月到我院接受治疗的92例类风湿关节炎,随机分为两组,对照组采用甲氨蝶呤治疗,观察组采用艾拉莫德联合甲氨蝶呤治疗,考察患者的治疗效果,生化指标情况,炎症水平情况和不良反应发生情况。结果观察组的治疗总有效率(93.02%)显著高于对照组(69.57%);两组患者治疗前生化指标无显著差异,治疗后观察组患者的类风湿因子、C反应蛋白、抗环瓜氨酸肽抗体、红细胞沉降率显著低于对照组;两组患者治疗前炎症水平无显著差异,治疗后观察组患者的免疫球蛋白G、白细胞介素-6、淋巴细胞绝对值显著低于对照组;观察组的不良反应发生率(13.04%)和对照组(17.39%)无统计学差异。结论类风湿关节炎应用艾拉莫德联合甲氨蝶呤治疗的有效性良好。

Objective To explore the effectiveness of the combination of Elamode and methotrexate in the treatment of rheumatoid arthritis.Methods 92 cases of rheumatoid arthritis treated in our hospital from December 2017 to December 2018 were randomly divided into two groups.The control group was treated with methotrexate,while the observation group was treated with Elamode combined with methotrexate.The therapeutic effect,biochemical indicators,inflammation level and adverse reactions of the patients were investigated.Results The total effective rate of the observation group(93.02%)was significantly higher than that of the control group(69.57%).There was no significant difference in the biochemical indexes before treatment between the two groups.After treatment,the rheumatoid factor,C-reactive protein,anti-cyclic citrullinated peptide antibody and erythrocyte sedimentation rate of the observation group were significantly lower than those of the control group.There was no significant difference in the level of inflammation before treatment between the two groups.The absolute values of white G,interleukin-6 and lymphocyte were significantly lower than those of the control group.There was no significant difference in the incidence of adverse reactions between the observation group(13.04%)and the control group(17.39%).Conclusion Rheumatoid arthritis treated with Iramode combined with methotrexate is effective.