沙丁胺醇联合酮替芬治疗小儿喘息性支气管炎的临床效果观察

Clinical Effect of Salbutamol combined with Ketotifen in the Treatment of Asthmatic Bronchitis in Children

目的观察并评价采用沙丁胺醇联合酮替芬对小儿喘息性支气管炎进行治疗的临床治疗效果,以方便为临床治疗工作提供有价值的依据。方法本文所选择的研究对象来自我院在2017年12月至2018年11月收治的小儿喘息型支气管炎患儿,本文选择86例患儿作为研究对象,采用随机方法将所有患儿分为常规治疗组和联合治疗组,每组平均为43例。对两组患儿均配合基础治疗,同时对常规治疗组患儿选择沙丁胺醇进行治疗,联合治疗组则采用沙丁胺醇联合酮替芬进行治疗,对两组患儿治疗以后的临床治疗状况进行比较。结果经过不同的治疗以后,常规治疗组的治疗总有效率为79.07%(34/43),联合治疗组为97.67%(42/43),P<0.05;常规治疗组的不良反应发生率为6.98%(3/43),联合治疗组为9.30%(4/43),P>0.05,差异不存在统计学意义;评价两组患儿治疗以后的咳喘消失时间、咳嗽消失时间、哮鸣音消失时间和湿啰音消失时间,本文的联合治疗组都明显比常规治疗组更短,P<0.05,差异存在统计学意义。结论对小儿喘息性支气管炎进行治疗的过程中,配合采用沙丁胺醇联合酮替芬进行治疗,能有效的帮助患儿改善治疗效果,并且具有较好的安全性,帮助患儿大大的缩短相关临床症状的恢复时间,值得推广。

Objective To observe and evaluate the clinical effect of sarbutamol combined with ketotifen in the treatment of pediatric asthmatic bronchitis,so as to provide valuable basis for clinical treatment.Methods The study subjects selected in this paper were children with asthmatic bronchitis admitted to our hospital from December 2017 to November 2018.86 children were selected as the study subjects.All children were randomly divided into the conventional treatment group and the combined treatment group,with an average of 43 cases in each group.Both groups were treated with basic therapy,while salbutamol was selected for treatment in the conventional treatment group,and salbutamol combined with ketotifen was used for treatment in the combined treatment group.The clinical treatment status of the two groups was compared after treatment.Results After different treatments,the total effective rate was 79.07%(34/43)in the conventional treatment group and 97.67%(42/43)in the combined treatment group,P<0.05.The incidence of adverse reactions was 6.98%(3/43)in the conventional treatment group and 9.30%(4/43)in the combined treatment group,P>0.05,and the difference was not statistically significant.To evaluate the disappearance time of cough and asthma,disappearance time of cough,disappearance time of wheezing and disappearance time of wet rhonk in two groups of children after treatment,the combined treatment group in this paper was significantly shorter than the conventional treatment group,P<0.05,and the difference was statistically significant.Conclusion In the treatment of pediatric asthmatic bronchitis,the combination of salbutamol and ketotifen can effectively help children improve the treatment effect,and has a good safety,helping children greatly shorten the recovery time of related clinical symptoms,which is worthy of promotion.