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神经血管单元在缺血性脑水肿中作用机制和中药对其治疗的研究进展 被引量:7

Research progress on mechanism of neurovascular unit in ischemic cerebral edema and treatment of traditional Chinese medicine
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摘要 脑水肿是神经系统疾病常见的并发症之一,其最初是由脑缺血、颅内感染、颅脑外伤等疾病所引起的。其中在临床上,缺血性脑水肿的发病率尤为突出。近些年,神经血管单元成为神经系统的研究热点,不同细胞及细胞间的相互作用在脑水肿的作用越来越受到关注。本文就参与缺血性脑水肿的不同细胞来阐述其发病机制及中医药对其治疗的特色作一阐述。 Aim Cerebral edema is one of the common complications in neurological diseases.It was originally caused by diseases such as cerebral ischemia,intracranial infection and craniocerebral trauma.Among them,the incidence of ischemic cerebral edema is particularly prominent.In recent years,neurovascular units are the current research hotspots,and the interaction of different cells and cells in brain edema has received increasing attention.This article describes the pathogenesis of different cells in the neurovascular unit in ischemic cerebral edema and the characteristics of traditional Chinese medicine treatment.
作者 田方泽 宋文婷 姚明江 徐立 任钧国 王敏 刘建勋 TIAN Fang-ze;SONG Wen-ting;YAO Ming-jiang;XU Li;REN Jun-guo;WANG Min;LIU Jian-xun(Institute of Basic Medical Sciences of Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing Key Lab of Chinese Materia Pharmacology,Beijing 100091,China;Graduate School of Beijing University of Chinese Medicine,Beijing 100029,China)
出处 《中国药理学通报》 CAS CSCD 北大核心 2020年第6期759-762,共4页 Chinese Pharmacological Bulletin
基金 国家重点基础研究发展计划(973计划)(No 2015CB554405) 国家自然科学基金资助项目(No 81873041)。
关键词 脑水肿 神经血管单元 NUV 血脑屏障 卒中 中药 cerebral edema neurovascular unit NUV blood-brain barrier stroke traditional Chinese medicine
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