经皮内镜下胃造瘘术对肿瘤所致进食困难患者的治疗效果

Therapeutic effect of percutaneous endoscopic gastrostomy on patients with feeding difficulties caused by tumor

目的:探讨经皮内镜胃造瘘术(PEG)对肿瘤所致进食困难患者的治疗效果。方法:回顾性分析广西医科大学附属肿瘤医院收治的因肿瘤所致进食困难并采用PEG治疗的患者33例,并选取每一病例在病理类型相同、分期相近的患者作为对照组。分析两组治疗前、后营养状况,对疾病的缓解,肿瘤复发,经济和患者生活质量评分等方面来评价PEG对肿瘤所致进食困难患者的治疗效果。结果:与治疗前比较,PEG组治疗3个月后体重指数(Ibm)降低(P<0.01),而白蛋白、血红蛋白比较,差异无统计学意义(P>0.05);对照组治疗后Ibm、白蛋白、血红蛋白均降低(均P<0.05)。治疗3个月后,PEG组白蛋白、血红蛋白高于对照组(P<0.05)。PEG组中复发人数、平均住院费用少于对照组(P<0.05);PEG组患者生活质量评分优于对照组(P<0.05)。结论:PEG治疗能够帮助对肿瘤所致进食困难对患者有良好营养支持作用,能够改善患者预后,且经济便捷,提高患者生活质量。

Objective:To explore the therapeutic effect of percutaneous endoscopic gastrostomy(PEG)on patients with feeding difficulties caused by tumor.Methods:A retrospective analysis was conducted on 33 patients with feeding difficulties caused by tumor and treated with PEG in Guangxi Medical University Affiliated Tumor Hospital,and patient with the same pathological type and similar stage as eachPEG-treatedpatientswere selected as the control group.The nutritional status oftwo groups were analyzed.Disease relief,tumor recurrence,economic,and patient quality of life were scored to evaluate the therapeutic effectof PEG treatment on patients with tumor-induced eating difficulties.Results:Compared with beforetreatment,the expression of Ibm was decreased after3 months ofPEG treatment(P<0.01),but there were no significant difference in the expression of albumin and hemoglobinbefore and after treatment(P>0.05);the expression level of Ibm,albumin,and hemoglobin were decreased in control group after treatment(all P<0.05).After 3 months of treatment,the expression of albumin and hemoglobin in the PEG group were higher than those in the control group(P<0.05).The number of recurrence and the average cost of hospitalization in the PEG group were lower than those in the control group(P<0.05).The score of quality of life in the PEG group was better than that in the control group(P<0.05).Conclusion:PEG treatment can help patients with feeding difficulties caused by tumor to have a good nutritional support,it can improve the prognosis and quality of life of patients with economical and convenient value.