糖皮质激素性骨质疏松症的中医证型分布特点

Distribution characteristics of TCM syndromes of glucocorticoid-induced osteoporosis

目的:探讨糖皮质激素性骨质疏松症的中医证型分布特点。方法:选择2017年1月1日-2018年12月31日来东莞市中医院进行治疗的68例糖皮质激素性骨质疏松症患者作为此次研究对象,参照中医证型相关标准将每个患者归纳到不同的证型,探究糖皮质激素性骨质疏松症分布规律及其与相关发病因素的内在关联。结果:本研究纳入研究的68例糖皮质激素性骨质疏松症患者中,肾阳虚型17例,占比25.0%(17/68),肾阴虚型16例,占比23.52%(16/68),肾阴阳两虚型12例,占比17.64%(12/68),气滞血瘀型10例,占比14.70%(10/68),脾胃虚弱型13例,占比19.11%(13/68)。结论:糖皮质激素性骨质疏松症的中医证型分布以肾阳虚型为主,具体症候分型为腰膝酸软,冷痛乏力,腰弯驼背,舌淡,苔薄白,脉沉无力,其次是肾阴虚型,具体症候分型为腰膝酸软,五心潮热,头晕耳鸣,口咽干燥,舌红苔少,脉细而数。

Objective:To investigate the distribution characteristics of TCM syndromes of glucocorticoid-induced osteoporosis.Methods:68 patients with glucocorticoid-induced osteoporosis treated in our hospital from January 1,2017 to December 31,2018 were selected as the research subjects.Each patient was classified into different syndrome types according to relevant TCM syndrome type standards to explore the distribution of glucocorticoid-induced osteoporosis and its internal correlation with related pathogenesis factors.Results:Among the 68 patients with glucocorticoid osteoporosis included in this study,17 patients were with kidney Yang deficiency 25.0%(17/68),16 patients were with kidney Yin deficiency 23.52%(16/68),12 patients were with kidney Yin and Yang deficiency 17.64%(12/68),10 patients were with qi stagnation and blood stasis 14.70%(10/68),and 13 patients were with spleen and stomach weakness 19.11%(13/68).Conclusion:Glucocorticoid osteoporosis of the TCM syndrome type distribution is given priority to with kidney Yang deficiency type,the classification for the specific symptom includes lumbar debility,cold pain,lumbar kyphosis,pale tongue,moss thin white,pulse heavy weakness,it is followed by kidney Yin deficiency type,classification for the specific symptom includes lumbar debility,five zang heat,dizziness tinnitus,oropharynx,dry,red tongue less moss,fine and fast pulse.