摘要
目的:分析全前循环梗死患者的超早期溶栓延迟的因素,并提出改进建议。方法:对某院2015年8月~2019年6月收治的215例全前循环梗死患者的临床资料进行回顾,分析超早期溶栓延迟的危险因素。结果:本组患者超早期溶栓延迟发生率为28.84%,超早期溶栓延迟发生者中不良预后发生率高于未发生者,差异有统计学意义(P<0.05);超早期溶栓延迟发生者24∶00~05∶59时间段发病、独居、NIHSS评分≥15分、主要照护家属不了解超早期溶栓、发病地点离医院距离>5km、未拨打120急救电话、存在溶栓治疗禁忌症者构成比均高于未发生者,差异均有统计学意义(P<0.05),且经Logistic回归分析可知上述因素均是超早期溶栓延迟的独立危险因素。结论:全前循环梗死患者超早期溶栓延迟现象常见,且发生者预后不良风险高,24∶00~05∶59时间段发病、独居等均是其危险因素,需重点防控。
Objective:To analyze the factors of ultra-early delayed thrombolysis in patients with total anterior circulation infarction and put forward suggestions for improvement. Methods:The clinical data of 215 patients with total anterior circulation infarction admitted to a hospital from Aug 2015 to June 2019 were reviewed. The factors for delayed thrombolysis were analyzed. Results: The incidence rate of delayed early thrombolysis was 28.84%, and the incidence of adverse prognosis in patients with delayed early thrombolysis was significantly higher than those without delayed early thrombolysis, with a statistically significant difference(P<0.05). The ratios of delayed occurrence of ultra-early thrombolysis occurred in 24∶00~05∶59 time intervals, including onset, solitude, NIHSS score ≥15, primary care families are not aware of ultra-early delayed thrombolysis, distance from the onset site to hospital >5 km, no 120 emergency telephone calls, contraindication of thrombolytic therapy were higher than those of the non-occurrence group, with statistically significant differences(P<0.05). Logistic regression analysis showed that these factors were independent risk factors for delayed thrombolysis(P<0.05). Conclusion:Ultra-early delayed thrombolysis is common in patients with total anterior circulation infarction, and the risk of poor prognosis is high. Onset in 24∶00~05∶59 and solitary living and so on are the risk factors, which need to be focused on prevention and control.
作者
胡姣月
Hu Jiaoyue(Department of Neurology,Shenzhen Longhua District Central Hospital,Shenzhen 518110)
出处
《数理医药学杂志》
2020年第6期807-809,共3页
Journal of Mathematical Medicine
关键词
全前循环梗死
超早期溶栓
延迟
危险因素
total anterior circulation infarction
ultra-early thrombolysis
delay
risk factors