肝细胞癌微血管侵犯定义和病理分级标准

Microvascular invasion in hepatocellular carcinoma:Definition and criteria for pathological grading

肝细胞癌的预后与微血管侵犯(MVI)密切相关,近年来对于MVI的临床研究越来越多,但对于基础病理发展与争议的文献则较少。作为临床研究的基础,了解微血管侵犯的定义及病理分级的争议具有重要意义。旨在对MVI定义的发展历程进行回顾,复习现有文献,并对MVI病理分级标准的研究现状进行分析,探讨不同分级标准对于肝细胞癌术后复发的预测价值,为MVI的临床研究提供参考。

The prognosis of hepatocellular carcinoma(HCC)is closely associated microvascular invasion(MVI),and in recent years,more and more clinical studies have been conducted on MVI,but there are few articles on the development of basic pathology and related controversies.As the basis of clinical research,it is of great significance to understand the definition of MVI and the controversy over pathological grading.With reference to related articles,this article reviews the development history of the definition of MVI,analyzes the current status of the research on the criteria for pathological grading of MVI,and assesses the value of different criteria in predicting postoperative recurrence of HCC,so as to provide a reference for the clinical research on MVI.