脓毒症患者急性心肌损伤的危险因素分析

Risk factors of acute myocardial injury with sepsis

目的:探讨脓毒症患者急性心肌损伤的危险因素。方法:将209例脓毒症患者,根据入院时肌钙蛋白I,分为心肌损伤组和非心肌损伤组。比较两组患者临床资料,并将单因素分析提示有显著性差异的因素纳入多因素Logistic回归分析,寻找脓毒症患者急性心肌损伤的独立危险因素。结果:非心肌损伤组病死率显著低于心肌损伤组,差异有统计学意义(P<0.05)。白细胞、血清钠离子为脓毒症患者急性心肌损伤的独立危险因素。结论:临床上,脓毒症患者应该在积极控制感染的情况下,密切监测电解质,及早给予干预措施。

Objective:To investigate the risk factors of acute myocardial injury in patients with sepsis.Methods:209 patients were divided into myocardial injury group and non-myocardial injury group according to whether the level of troponin I during admission.After compared the clinical data between two groups,the factors showing significant difference from single factor analysis were included in multivariate Logistic regression analysis to find independent risk factors of acute myocardial injury in patients with sepsis.Results:The mortality rate in the non-myocardial injury group was significantly lower than that in the myocardial injury group(P<0.05).White blood cell counts and serum sodium ions were independent risk factors for acute myocardial injury in patients with sepsis.Conclusion:Early interventions should be provided and electrolyte levels should be monitored while actively controlling infections in clinic.