摘要
DNA甲基化是表观遗传学的一种重要修饰形式,也是一种重要的基因表达调控机制。DNA甲基化的异常模式可导致植物生长发育异常。文中从植物DNA甲基化模式入手,对DNA甲基化在调控基因表达和维持基因组稳定性的分子功能、DNA甲基化在植物发育、参与植物对生物和非生物胁迫的反应等方面的相关研究进行回顾和总结,为深入了解DNA甲基化的作用机制并将DNA甲基化应用于植物新品种的培育和遗传改良研究提供一定的参考。
DNA methylation is an epigenetic modification that forms an important regulation mechanism of gene expression in organisms across kingdoms.Aberrant patterns of DNA methylation can lead to plant developmental abnormalities.In this article,we briefly discuss DNA methylation in plants and summarize its functions and biological roles in regulating gene expression and maintaining genomic stability,plant development,as well as plant responses to biotic and abiotic stresses.We intended to provide a concise reference for further understanding of the mechanism of DNA methylation and potential applications of epigenetic manipulation for crop improvement.
作者
袁超
张少伟
牛义
汤青林
魏大勇
王志敏
Chao Yuan;Shaowei Zhang;Yi Niu;Qinglin Tang;Dayong Wei;Zhimin Wang(Key Laboratory of Horticulture Science for Southern Mountainous Regions Ministry of Education,College of Horticulture and Landscape Architecture,Southwest University,Chongqing 400715,China;Chongqing Key Laboratory of Olericulture,Chongqing 400715,China)
出处
《生物工程学报》
CAS
CSCD
北大核心
2020年第5期838-848,共11页
Chinese Journal of Biotechnology
基金
国家自然科学基金(No.31501756)
中央高校基本科研业务费专项(No.XDJK2018B039)
重庆市基础研究与前沿探索专项面上项目(No.cstc2019jcyj-msxmX0448)资助。
