加味丹栀逍遥散对中风后失眠患者睡眠质量及生活质量影响

Effect of Jiawei Danzhi Xiaoyao San on sleep quality and quality of life in patients with insomnia after stroke

目的探讨加味丹栀逍遥散对中风后失眠患者睡眠质量和生活质量的影响作用。方法选择2018年6月至2019年6月期间在陕西省核工业二一五医院就诊的92例中风失眠患者作为研究对象,按照随机数字表法分为研究组和对照组,每组46例,均给予常规内科治疗,对照组患者给予艾司唑仑片治疗,研究组患者给予加味丹栀逍遥散联合艾司唑仑片治疗,观察两组患者睡眠质量改善情况和治疗对生存质量和生活能力的影响。结果研究组患者治疗后临床总有效率为93.48%,显著高于对照组71.74%(P<0.05);治疗后两组患者睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍和匹斯堡睡眠质量指数量表(PSQI)总得分均显著降低(P<0.05),研究组以上指标均显著低于对照组(P<0.05);治疗后两组患者世界卫生组织生存质量评定量表简表(WHOQOL-BREF)评分和日常生活能力量表(ADL)评分均较治疗前显著升高(P<0.05),研究组以上指标均显著高于对照组(P<0.05)。结论使用加味逍遥散联合常规西药的方法治疗中风后失眠患者可有效改善患者睡眠质量,提高生存质量和生活质量,进而提高治疗效果,其作用显著,可推广使用。

Objective To investigate the effect of Jiawei Danzhi Xiaoyao San on sleep quality and quality of life in patients with stroke and insomnia.Methods 92 patients with stroke and insomnia admitted to the hospital from June 2018 to June 2019 were enrolled in the study.According to the random number table method,46 patients in the study group and the control group were given conventional medical treatment.The patients in the control group were treated with estazolam tablets.The patients were treated with Jiaweidanzhixiaoyaosan and estazolam tablets.The improvement of sleep quality and the effect on quality of life were observed.Results The total effective rate of the study group was 93.48%,which was significantly higher than that of the control group(71.74%,P<0.05).After treatment,the sleep quality,sleeping time,sleep time,sleep efficiency,sleep disorders,hypnotic drugs,daytime dysfunction and Pittsburgh sleep quality index scale(PSQI)total scores were significantly lower.The above indexes in the study group were significantly lower than those in the control group(P<0.05).After treatment,the life quality assessment scale of World Health Organization(WHOQOL-BREF)score and ability of daily living scale(ADL)score were significantly increased.The above indexes in the study group were significantly higher than those in the control group(P<0.05).Conclusion The combination of Jiawei Danzhi Xiaoyao San on the treatment of insomnia after stroke can improve the quality of life and quality of life,and improve the therapeutic effect.It can be promoted and used.