七氟烷麻醉骨折老年患者苏醒期躁动应用右美托咪定的临床效果

The clinical effect of dexmedetomidine in the treatment of restlessness at revival stage in the elderly patients with fracture under sevoflurane anesthesia

目的:观察右美托咪定对七氟烷麻醉骨折老年患者苏醒期躁动的临床效果。方法:选取2013年5月-2019年5月行骨折手术的老年患者500例,随机分为两组,各250例。两组均以七氟烷进行麻醉;手术结束前,研究组给予1μg/kg右美托咪定静脉滴注,常规组给予等量生理盐水静脉滴注。比较两组患者躁动发生率、Riker镇静躁动(RSAS)评分及疼痛(VAS)评分。结果:研究组用药后VAS评分及RSAS评分均明显低于常规组,研究组躁动发生率低于常规组,差异有统计学意义(P<0.05)。结论:右美托咪定应用于七氟烷麻醉骨折老年患者苏醒期躁动,能有效降低患者疼痛及躁动评分,同时减少躁动情况的发生。

Objective:To explore the clinical effect of dexmedetomidine in the treatment of restlessness at revival stage in the elderly patients with fracture under sevoflurane anesthesia.Methods:From May 2013 to May 2019,500 elderly patients with fracture surgery were selected and randomly divided into two groups with 250 cases in each group.Both groups were anesthetized with sevoflurane.Before the end of the operation,the study group was given 1μg/kg dexmedetomidine intravenous drip,and the conventional group was given the same amount of normal saline intravenous drip.We compared the incidence of agitation,Riker sedation agitation(RSAs) score and pain(VAS) score between the two groups.Results:In the study group,VAS score and RSAs score after medication were significantly lower than those in the conventional group,and the incidence of agitation was also lower than that in the conventional group,the difference was statistically significant(P<0.05).Conclusion:The application of dexmedetomidine in the treatment of restlessness at revival stage in the elderly patients with fracture under sevoflurane anesthesia can effectively reduce the score of pain and restlessness and reduce the occurrence of restlessness.