阿昔洛韦联合纳洛酮治疗病毒性脑炎的效果分析

Effect of acyclovir combined with naloxone in the treatment of viral encephalitis

目的:探讨阿昔洛韦联合纳洛酮治疗病毒性脑炎的效果。方法:2017年7月-2019年7月收治病毒性脑炎患者76例,随机分为两组,各38例。阿昔洛韦组采用阿昔洛韦,联合组采用阿昔洛韦联合纳洛酮治疗,比较两组治疗效果。结果:联合组治疗后血清NSE水平低于阿昔洛韦组,差异有统计学意义(P<0.05)。联合组治疗总有效率高于阿昔洛韦组,差异有统计学意义(P<0.05)。结论:阿昔洛韦联合纳洛酮治疗病毒性脑炎,能够更好发挥两种药物的药理作用,可以积极改善脑部神经功能,有效控制并缓解病情。

Objective:To explore the effect of acyclovir combined with naloxone in the treatment of viral encephalitis.Methods:From July 2017 to July 2019,76 patients with viral encephalitis were selected and randomly divided into two groups with 38 cases in each group.The acyclovir group was treated with acyclovir.The combination group was treated with acyclovir and naloxone.We compared the efficacy of the two groups.Results:After treatment,the serum NSE level in the combination group was lower than that in the acyclovir group,the difference was statistically significant(P<0.05).In the combination group,the total effective rate was higher than that in the acyclovir group,the difference was statistically significant(P<0.05).Conclusion:Acyclovir combined with naloxone in the treatment of viral encephalitis can better play the pharmacological role of the two drugs,can actively improve the brain nerve function,effectively control and alleviate the disease.