酮咯酸氨丁三醇对老年骨科手术后睡眠质量的影响

Effect of Ketorolac Tromethamine on Sleep Quality after Orthopedic Surgery in Elderly Patients

目的:探讨酮咯酸氨丁三醇对老年骨科手术后患者睡眠质量的影响。方法:选取2017年6月至2018年12月山东省日照市莒县人民医院骨科收治的老年骨折患者84例作为研究对象,随机分为观察组和对照组,每组42例。2组患者进行常规手术治疗,对照组术后静脉泵入舒芬太尼1.5~2.5 g/kg加托烷司琼5 mg;观察组术后在对照组用药治疗的基础上口服酮咯酸氨丁三醇,1粒/次,3次/d;对2组患者的睡眠质量进行评分,比较2组患者入睡潜伏期、觉醒次数、睡眠时间的差异。结果:观察组术后睡眠质量评分与术前比较,差异无统计学意义(P>0.05),对照组术后与术前比较,差异有统计学意义(P<0.05),术后2组患者睡眠质量评分比较,差异有统计学意义(P<0.05)。观察组患者需要(33.8±4.7)min入睡,且持续睡眠时间是(5.8±1.2)h,中间平均觉醒次数在(1.8±0.6)次;对照组需要(45.7±5.3)min入睡,且持续睡眠时间是(4.4±0.9)h,中间平均觉醒次数在(3.9±1.2)次;2组患者睡眠相关指标比较,差异有统计学意义(P<0.05)。结论:酮咯酸氨丁三醇可有效改善老年患者骨科术后睡眠情况,提高睡眠质量。

Objective:To investigate the effect of Ketorolac Tromethamine on sleep quality in elderly patients after orthopedic surgery.Methods:A total of 84 elderly patients with fractures admitted from June 2017 to December 2018 were randomly divided into observation group and control group,with 42 cases in each group.Patients in the two groups were treated with routine surgery before surgery,while patients in the control group were intravenously pumped with sufentanil 1.5~2.5 g/kg and troxisetron 5 mg after surgery.Observation group on the basis of the control group,oral Ketorolac Tromethamine,one at a time,3 times a day;Sleep quality was scored,and differences in sleep latency,number of awakenings and sleep duration were recorded.Results:The sleep quality score of the two groups showed no statistical difference between the observation group and the preoperative group(P>0.05),while there was a statistical difference between the control group and the preoperative group(P<0.05),while there was a statistical difference between the two groups(P<0.05).In the observation group,patients needed(33.8±4.7)min to fall asleep,and the duration of sleep was(5.8±1.2)h.The average number of awakenings was(1.8±0.6)times.The control group needed(45.7±5.3)min to fall asleep,and the duration of sleep was(4.4±0.9)h.The average number of awakenings was(3.9±1.2)times.The difference of sleep parameters between the two groups was statistically significant(P<0.05).Conclusion:Ketorolac Tromethamine can effectively improve the sleep status and duration of the elderly patients after orthopedic surgery.