288例宫内死胎原因分析及防治措施探讨

Cause of stillbirth in 288 cases and its prevention and treatment

目的:探讨宫内死胎的原因,针对其提出相应的干预措施,以降低死胎的发生。方法:收集2007年12月至2018年1月在桂林医学院附属医院病理科收集到的桂北地区胎儿尸检病例共288例,对与死胎有关的母婴相关因素进行回顾性分析。结果:288例死胎发生原因胎儿畸形96例,宫内窒息77例,感染性疾病27例,染色体异常26例,出血性疾病25例,不明死因26例,母体主观因素11例。前三位死因的临床病理符合率分别是90.60%、76.19%、33.33%。结论:加强围产期保健宣教、孕期保护、定期产检以及对母体疾病进行积极干预治疗有助于减少死胎的发生。

Objective:To explore the causes of intrauterine stillbirth and to put forward corresponding intervention measures to reduce the occurrence of stillbirth.Methods:A total of 288 fetal autopsy cases were collected from the department of pathology of the affiliated hospital of guilin medical college from December 2007 to January 2018.Maternal and infant factors related to stillbirths were retrospectively analyzed.Results:Causes of 288 stillbirths:96 cases of fetal malformation,77 cases of intrauterine asphyxia,27 cases of infectious diseases,26 cases of chromosomal abnormalities,25 cases of hemorrhagic diseases,26 cases of unexplained causes of death,and 11 cases of maternal subjective factors.The clinicopathological coincidence rates of the top three causes of death were 90.60%,76.19%and 33.33%,respectively.Conclusion:Strengthening perinatal health education,prenatal protection,regular prenatal check-up and active intervention for maternal diseases can reduce the incidence of stillbirth.