加味寿胎方改善黄体酮治疗先兆流产的临床疗效观察

Clinical observation on Modified Shoutai Prescription for improving progesterone in the treatment of threatened abortion

目的:本研究旨在通过使用黄体酮与加味寿胎方的联合疗法,对单一黄体酮疗法进行改进。方法:选取2016年5月至2017年1月在湖南省妇幼保健院就诊的94例先兆流产患者作为研究对象,并分为44例对照组(黄体酮20mg/d,肌肉注射)和50例治疗组(在对照组的基础上给予加味寿胎方治疗)。结果:7d后,血清样本β-HCG水平定量测定实验表明,治疗组患者接受加味寿胎丸联合黄体酮治疗后,血清β-HCG水平较治疗前呈显著上升(P<0.01),并且β-HCG的增比水平明显高于对照组(P<0.05)。结论:加味寿胎方联合黄体酮注射液治疗先兆流产的疗效明显优于单独应用黄体酮,这种联合疗法对临床治疗先兆流产具有一定的指导意义。

Objective:The purpose of this study is to improve the single progesterone therapy by using the combined therapy of progesterone and modified Shoutai Formula.Methods:Ninety-four threatened abortion patients treated in Hunan Maternal and Child Health Hospital from May 2016 to January 2017 were selected as the study subjects and divided into 44 cases in control group(progesterone 20 mg/day,intramuscular injection)and 50 cases in treatment group(on the basis of the control group,treated with modified Shoutai Formula).Results:After 7 days,the level ofβ-HCG in serum was quantified.The results showed that the serum levels ofβ-HCG in the treatment group were significantly higher than that before treatment(P<0.01),and the increasedβ-HCG ratio was significantly higher than that in control group(P<0.05).Conclusion:The effect of Shoutai Formula Recipe combined with progesterone injection in treating threatened abortion is obviously better than that of progesterone alone.This combination therapy has certain guiding significance for clinical treatment of threatened abortion.