基因检测联合专人管理在冠心病介入术后患者中的应用效果

Application effect of genetic testing combined with dedicated personnel management in patients after coronary heart disease interventional operation

目的探讨基因检测联合专人管理在冠心病介入术后患者中的应用效果。方法选取2016年10月至2017年3月在我院心内科、CCU住院行经皮冠状动脉介入术(PCI)的125例患者为研究对象,按是否进行基因检测及不同随访方法分为观察组63例和对照组62例。对照组住院期间给予常规治疗指导用药,传统当班责任护士健康宣教及出院后电话随访模式;观察组在对照组基础上采用基因检测联合专人管理。两组患者随访15个月。比较两组患者服药依从性、再住院率及心血管不良事件发生率和护理满意度。结果住院时两组患者服药依从性评分比较差异无统计学意义(P>0.05),出院后第6,12,15个月,观察组患者服药依从性评分均高于对照组(P<0.05)。观察组心血管事件发生率和再住院率均低于对照组(P<0.05)。观察组患者护理满意度高于对照组(P<0.05)。结论基因检测联合专人管理可以有效提高冠心病介入术后患者服药依从性、减少再住院率及心血管不良事件发生率,提高护理满意度。

Objective To investigate the application effect of genetic testing combined with dedicated personnel management in patients after coronary heart disease interventional operation.Methods To select 125 cases of patients who were admitted to the cardiology department and CCU of our hospital for percutaneous coronary intervention(PCI)from October 2016 to March 2017 as the study subjects,and they were divided into an observation group for 63 cases and a control group for 62 cases according to whether genetic testing and different follow-up methods were performed.The control group was given routine treatment for guiding medication,the traditional health education carried out by primary nurse on duty during hospitalization and the telephone follow-up mode after discharge from the hospital.The observation group was adopted by genetic testing combined with dedicated personnel management on the basis of the control group.The patients of the two groups were followed up for 15 months.The medication compliance,re-hospitalization rate,incidence of cardiovascular adverse events and nursing satisfaction were compared between the two groups.Results There was no significant difference in score of medication compliance in the hospitalization period between the two groups(P>0.05).At 6,12,and 15 months after discharge,the scores of medication compliance of the observation group were higher than those of the control group(P<0.05).The incidence of cardiovascular events and re-hospitalization rate in the observation were lower than those in the control group(P<0.05).The nursing satisfaction in the observation group was higher than that in the control group(P<0.05).Conclusion The application of genetic testing combined with dedicated personnel management can effectively improve the medication compliance of patients after coronary heart disease interventional operation,reduce the re-hospitalization rate and the incidence of cardiovascular adverse events,and improve the nursing satisfaction.