热毒宁联合阿莫西林-克拉维酸钾对小儿支气管肺炎的临床疗效评价

Clinical evaluation of Reduning combined with amoxicillin and clavulanate potassium in the treatment of bronchopneumonia in children

目的探讨热毒宁与阿莫西林-克拉维酸钾联用对小儿支气管肺炎的临床疗效。方法86例小儿支气管肺炎患儿,随机分为观察组和对照组,每组43例。两组均接受常规治疗,对照组在常规治疗基础上接受阿莫西林-克拉维酸钾治疗,观察组在常规治疗基础上给予热毒宁联合阿莫西林-克拉维酸钾治疗。观察两组治疗前后白细胞计数水平、临床症状评分、临床症状恢复正常时间、临床疗效。结果治疗后,观察组白细胞计数水平(7.16±1.81)×10^9/L、临床症状评分(2.65±0.81)分均低于对照组的(9.55±2.94)×10^9/L、(4.14±1.74)分,差异均有统计学意义(P<0.05)。观察组体温、咳嗽、呼吸不畅、肺部啰音恢复正常时间分别为(2.34±0.02)、(2.32±0.98)、(2.43±0.52)、(2.02±0.56)d,均短于对照组的(3.67±1.78)、(4.42±1.12)、(4.21±1.65)、(3.94±1.63)d,差异有统计学意义(P<0.05)。观察组治疗总有效率97.67%显著高于对照组的86.05%,差异有统计学意义(P<0.05)。结论热毒宁与阿莫西林-克拉维酸钾治疗小儿支气管肺炎具有重要意义,可以促进小儿肺炎症状的恢复,临床效果满意。

Objective To discuss the clinical efficacy of Reduning combined with amoxicillin and clavulanate potassium in the treatment of bronchopneumonia in children.Methods A total of 86 children with bronchopneumonia were randomly divided into observation group and control group, with 43 cases in each group. The control group was treated by amoxicillin and clavulanate potassium on the basis of conventional therapy, and the observation group was treated by Reduning combined with amoxicillin and clavulanate potassium on the basis of conventional therapy. The white blood cell count and clinical symptom score before and after treatment, recovery time of clinical symptom and clinical efficacy were compared between the two groups. Results After treatment, the white blood cell count (7.16±1.81)×10^9/L and clinical symptom score (2.65±0.81) points of the observation group were lower than those of the control group (9.55±2.94)×10^9/L and (4.14±1.74) points, and the difference was statistically significant (P<0.05). The recovery time of body temperature, cough, dyspnea and lung rales of the observation group were (2.34±0.02), (2.32±0.98), (2.43±0.52) and (2.02±0.56) d respectively, which were all shorter than those of the control group (3.67±1.78), (4.42±1.12), (4.21±1.65) and (3.94±1.63) d, and the difference was statistically significant (P<0.05). The total effective rate of treatment 97.67% of the observation group was significantly higher than that of the control group 86.05%, and the difference was statistically significant (P<0.05). Conclusion Reduning injection combined with amoxicillin and clavulanate potassium is of great significance in the treatment of pneumonia in children, which can promote the recovery of children’s pneumonia symptoms, and the clinical effect is satisfactory.