摘要
碳点是一种具有优异荧光性质的新兴纳米材料。相比于传统的有机染料和半导体量子点,碳点具有毒性低和生物相容性好等优点。目前,碳点在分析检测、荧光成像、药物运载等诸多领域有着广泛的应用。鹿茸是一味具有多种药效的传统名贵中药,也是罕见的具备再生能力的哺乳动物器官。鹿茸的生物学特性和药效与其化学成分有着密切联系。简要综述了碳点在荧光检测、荧光成像以及光诊疗方面的应用进展,对碳点应用于鹿茸生物学特性及其化学成分分析研究的可行性进行了探讨。
Carbon dots are an emerging nanomaterial with excellent fluorescent properties.Compared with traditional organic dyes and semiconductor quantum dots,carbon dots possess advantages of low toxicity and good biocompatibility.At present,carbon dots are widely used in many fields such as analytical detection,fluorescence imaging and drug delivery.Cervi Cornu Pantotrichum,a rare mammalian organ with ability of full regeneration,has been used as famous traditional Chinese medicine.The biological functions and efficacy of Cervi Cornu Pantotrichum are closely related to their chemical constituents.In this paper,we briefly reviewed the progress of carbon dots research in fluorescence detection,fluorescence imaging and phototherapy,carried out the bioimaging and cell cytotoxicity test by carbon dots,and discussed the feasibility of carbon dots in biological features and chemical composition analysis of Cervi Cornu Pantotrichum.
作者
徐源
李春义
赵海平
XU Yuan;LI Chun-yi;ZHAO Hai-ping(State Key Laboratory for Molecular Biology of Special Economic Animals,Deer Antler Engineering Research Center,Institute of Special Animal and Plant Sciences of CAAS,Changchun 130112,China;Changchun Sci-Tech University,Changchun 130600,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第9期2580-2586,共7页
Chinese Traditional and Herbal Drugs
关键词
鹿茸
碳点
荧光检测
活性物质
光诊疗
生物学特性
Cervi Cornu Pantotrichum
carbon dots
fluorescence detection
active substance
phototherapy
biological characteristics