葛花水提物的抗疲劳作用的研究

Study on anti-fatigue effect of water extract from pueraria lobata

目的考察葛花水提物的抗疲劳作用.方法将健康昆明种小鼠,随机平均分成4组,灌胃给葛花提取物的高、中、低三个浓度组及空白对照组.连续给药15d后分别进行疲劳转棒实验测试和负重游泳实验测定,并测定小鼠的肝糖原含量.结果给药组较对照组均有增加运动耐力时间、游泳时间、肝糖原含量的作用.结论葛花水提取物具有明显的抗疲劳作用.

Objective To investigate the anti-fatigue effect of aqueous extract of Pueraria lobata.Methods The healthy Kunming mice were randomly divided into 8 groups,and the high,middle and low concentration groups and the blank control group were given the extract of Pueraria lobata by gavage.After 15 days of continuous administration,fatigue rotating rod test and weight-bearing swimming test were carried out to determine the content of hepatic glycogen in mice.Results The exercise endurance time,swimming time and hepatic glycogen content were increased in the administration group compared with the control group.Conclusion The water extract of Pueraria lobata has obvious anti-fatigue effect.