水囊在妊娠合并肝功能异常孕妇中期引产中的临床应用

Clinical Application of Water Sac in Mid-term Induction of Labor in Pregnant Women with Abnormal Liver Function

目的评价水囊使用于妊娠同时存在肝功能异常孕妇中期引产过程中的引产效果以及引产安全情况。方法方便选取2017年5月—2019年8月该院收入且实行中期引产的64例妊娠同时存在肝功能异常孕妇(孕周处于14周到27周)予以该次项目统计,予以分组的方式选择随机双盲方式,各32例,试验组应用水囊中期引产方法,对照组应用米非司酮+米索前列醇中期引产方法,且两组都予以临床保肝治疗,对孕妇产程总时长、出血总时长、出血总量、住院总天数、中期引产成功合计值、引产不良反应合计值实行评比。结果试验组孕妇产程总时长、出血总时长、出血总量[(58.35±3.60)h、(2.70±0.34)d、(60.57±5.10)mL]对比对照组统计数据结果[(57.10±3.72)h、(2.84±0.40)d、(61.30±5.26)mL],数值间差异无统计学意义(t=1.365、1.508、0.563,P>0.05),试验组孕妇住院总天数[(7.30±1.24)d]较对照组统计数据结果[(13.36±2.50)d]缩短,数值间差异有统计学意义(t=12.284,P<0.05);试验组孕妇中期引产成功合计值(90.62%)对比对照组统计数据结果(96.87%),数值间差异无统计学意义(χ2=1.066,P>0.05);试验组孕妇引产不良反应合计值(0.00%)较对照组统计数据结果(12.50%)降低,数值间差异有统计学意义(χ2=4.266,P<0.05)。结论在妊娠同时存在肝功能异常孕妇中期引产过程中运用水囊展现较优临床引产效果,同时孕妇无不良反应表现,存在较高引产安全程度。

Objective To evaluate the effect of induction of labor and safety of labor during mid-term induction of labor with pregnant women with liver dysfunction.Methods From May 2017 to August 2019,64 cases of pregnant women with liver dysfunction and pregnancy with liver function abnormalities during the mid-term induction of labor were convenient selection included in this project.The method of grouping was selected.In a randomized double-blind method,32 patients were enrolled in each group.The experimental group used the mid-term induction of labor with water sac and the control group applied the mid-term induction of induction with mifepristone+misoprostol.The two groups were treated with clinical liver protection.The total length of labor,the total length of bleeding,the total amount of bleeding,the total number of days in hospital,the total value of successful mid-term induction of labor,and the total value of adverse reactions to induction of labor were evaluated.Results The total length of labor,total bleeding time,and total bleeding[(58.35±3.60)h,(2.70±0.34)d,(60.57±5.10)mL]of pregnant women in the test group compared with the statistical results of the control group[(57.10±3.72)h,(2.84±0.40)d,(61.30±5.26)mL],The difference was not statistically significant(t=1.365,1.508,0.563,P>0.05),the total number of days of hospitalization of pregnant women in the test group[(7.30±1.24)d]compared with the statistical results of the control group[(13.36±2.50)d]shortened,The difference was statistically significant(t=12.284,P<0.05);the total successful mid-term induction of labor in the experimental group(90.62%)compared with the control group(96.87%),The difference was not statistically significant(χ2=1.066,P>0.05);the total value of adverse reactions to induction of pregnancy in the experimental group(0.00%)was lower than that in the control group(12.50%),and the values were different.The difference was statistically significant(χ2=4.266,P<0.05).Conclusion The use of a water bladder during mid-term induction of labor in pregnant women with liver dysfunction at the same time shows a better clinical induction of labor.At the same time,there are no adverse reactions in pregnant women,and there is a high degree of labor induction safety.